...All source code remains on your device and integrates seamlessly with your preferred IDE. A natural-language API enables powerful data queries and updates, automating tasks without leaving the chat interface. By running entirely locally, Dyad delivers maximum privacy, minimal latency, and smooth developer experiences free from cloud-based inconsistencies.
This project will help researchers to implement Population Density Approach in order to find the The Most Likely Configuration among all possible using TMoLiC software. This approximation was created to establish initially the Asp Dyad protonation state of Aspartyl Proteases. However, the concept can be expand to proteins in general to aboard conformational changes or protonation state problems.
For more deatils regarding Population Density concept, please read:
https://doi.org/10.1080/07391102.2017.1393461
and
https://doi.org/10.1016/j.jmgm.2016.10.006