Hill Finder
Detection of Proximal RNA Binding Sites in HITS Data
High-throughput sequencing has been widely used to find novel protein-binding RNAs, utilizing methods such as CLIP-Seq and Genomic SELEX. Typical analyses of the high-throughput data employ the use of a histogram of the aligned read count per base, the intensity of which indicates, for a specific region of an RNA, the underlying sequence's relative occurrence of binding events in the experiment. This technique can, however, obscure the precise locations of binding sites in close proximity...