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The Pure Data (short Pd) project on SourceForge unifies the extensions (or externals) written for the Pure Data Graphical Computer Music System written by Miller Puckette with contributions from many others.
Realtime 3D game/visualization engine, written in C++, scriptable through Tcl/Tk, Python and Lua. Supports D3D and OpenGL for rendering, runs under Linux and Windows.
Open Source and Portable object oriented software for 3D digital image segmentation and visualization. Pipes and Filters Architechture.
Implemented in C++, and uses FLTK, VTK, ITK, TCL (plugins), and pipeline filters implemented in XML. DICOM support.
...The system includes specifications for a client engine and 2 protocols. Demo apps: mud/moo proxy, tetris. Currently uses OpenGL, VRML, java, tcl. Client/server architecture for security.