Product snapshot

Rejoyn is a digital therapeutic app designed to be used alongside prescription antidepressant medication. Intended for adults 22 and older, the program combines short brain-training activities with skills-based therapy lessons delivered across a six-week course. The tool is authorized by the U.S. Food and Drug Administration as a medical device and is intended to strengthen the effects of antidepressant treatment by leveraging neuroplasticity. Typical engagement is under two hours per week, and users have not reported side effects attributable to the app itself.

Who this is for and how to get it

  • Rejoyn is intended for adults (age 22+) who are already taking antidepressant medication.
  • A clinician’s prescription is required to access the app, ensuring it is integrated with an individual’s current treatment plan.
  • It should be considered a complementary therapy rather than a replacement for medications or other professional care.

How the program works

The app delivers a mix of short, focused cognitive exercises and practical therapy lessons that aim to encourage beneficial brain changes. The six-week structure provides a time-limited course of training, with brief weekly sessions so users can fit the program into routine life without a large time commitment.

Evidence and development

Rejoyn was developed by clinicians and researchers in psychology, psychiatry, and neuroscience and was evaluated in a phase 3 clinical trial. That study demonstrated its effectiveness as an adjunctive treatment for Major Depressive Disorder when used alongside standard antidepressant medication. The FDA authorization reflects its status as a regulated medical device.

Key points at a glance

  • Requires a prescription from a healthcare provider.
  • Authorized by the U.S. Food and Drug Administration as a medical device.
  • Supported by phase 3 clinical trial data as an adjunct treatment for MDD.
  • Created by a multidisciplinary team of mental health and neuroscience professionals.
  • Delivered as a six-week program of exercises and lessons.
  • Typical use is under two hours per week.
  • Intended for adults aged 22 and over who are taking antidepressants.
  • Designed to augment medication effects by promoting neuroplasticity.
  • No app-specific side effects have been reported in available information.
  • Not meant to be used as a standalone treatment for depression.

Alternative option

  • RSQ Physio — Free: an alternative digital option that may be worth discussing with your healthcare provider.

Technical

Title
Rejoyn
Requirements
  • iPhone
Language
No language has been specified.
Available languages
License
  • Free
Latest update
2026-01-10
Author
Otsuka Precision Health Inc.
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