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#2659 protein processing

TermGenie
closed-duplicate
nobody
None
5
2005-07-26
2005-07-05
No

I'm trying to work out what distinguished protein
processing from protein modification?

SGD have a GPI biosyntheis protein YCL052C annotated
to protein processing.

Should GPI biosynthesis (and other things like this) be
a child of this term.....

Discussion

  • John S. Garavelli

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    Wouldn't "protein processing" include the process of
    translocation? Translocation usually, but not necessarily,
    involves the process of "protein modification" which would
    be the covalent and conformational changes.

     
  • Becky Foulger

    Becky Foulger - 2005-07-11

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    See also SF:1150967 (which can be completed after the
    discussion about the difference between protein processing
    and protein modification is resolved)

    And SF: 1000275 ['protein processing' - update definition]

     
  • Valerie Wood

    Valerie Wood - 2005-07-11

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    OK, can close this if it is a duplicate ...but I can't find
    SF: 1000275 ['protein processing' - update definition]

     
  • Harold J. Drabkin

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    It is not clear what is meant by "biosynthesis", since the current defintion of
    "protein biosynthesis" and it's children could include everything from
    translation through post-translatinal modifications.

    Also, translocation is also used to mean the transfer of the growing
    polypeptide chain from A to P site on the ribosome , in addtion to traversing
    a membrane! I never liked that term.

     
  • Jane Lomax

    Jane Lomax - 2005-07-26
    • status: open --> closed
     
  • Jane Lomax

    Jane Lomax - 2005-07-26
    • milestone: --> TermGenie
    • status: closed --> closed-duplicate
     

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