The suite QueTAL was developed to offer tailored tools for comparison of TAL effector genes. The program DisTAL considers each repeat as a unit, transforms a TAL effector sequence into a sequence of coded repeats and makes pair-wise alignments between these coded sequences to construct trees. The program FuncTAL is aimed at finding TAL effetors with similar DNA-binding capabilities. It calculates correlations between positional weight matrices obtained from the RVD sequence, and builds trees based on these correlations. The programs accurately represented phylogenetic and functional relations between TAL effectors using either simulated or literature-curated data.

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2015-04-17