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#1414 increased urinary mineral level synonyms
Consider adding the synonym X wasting for the terms
increased urine calcium level (i.e. calcium wasting)
increased urine magnesium level
increased urine potassium level
See J:159706 for calcium and magnesium
See OMIM (241200 and others) for potassium also http://www.nlm.nih.gov/medlineplus/ency/article/000308.htm Medline Plus article
HPO has a term called Renal Potassium wasting (undefined). So we may want to make the synonym renal X wasting
Dear Sue and colleagues,
I have provided a definition for renal potassium wasting. This is something that is measured in certain medical contexts:
Definition: High urine potassium in the presence of hypokalemia.
Comment: A urine potassium assay can be used to determine the cause of reduced serum potassium (hypokalemia). Normally, the kidney will reabsorb more potassium in the presence of hypokalemia. Therefore, a low urine potassium can suggest gastrointestinal potassium loss, poor dietary intake, or a shift of potassium from the extracellular to the intracellular space. On the other hand, a high urine potassium in the face of low serum potassium indicated renal loss, referred to as renal potassium wasting.
So therefore the terms are not synonymous. I see that the HPO hierarchy in this section could use with a bit of revision, perhaps the MP and the HP could group up to make sure there are correct correspondences wherever possible?
-Peter
Dr. med. Peter N. Robinson, MSc.
Professor of Medical Genomics
Professor in the Bioinformatics Division of the Department of Mathematics and Computer Science of the Freie Universität Berlin
Institut für Medizinische Genetik und Humangenetik
Charité - Universitätsmedizin Berlin
Augustenburger Platz 1
13353 Berlin
Germany
+4930 450566006
Mobile: 0160 93769872
peter.robinson@charite.de
http://compbio.charite.de
http://www.human-phenotype-ontology.org
Introduction to Bio-Ontologies: http://www.crcpress.com/product/isbn/9781439836651
I have learned from my mistakes, and I am sure I can repeat them exactly
ORCID ID:http://orcid.org/0000-0002-0736-9199
Scopus Author ID 7403719646
Von: Sue Bello [suebello@users.sf.net]
Gesendet: Mittwoch, 2. Oktober 2013 22:34
An: [obo:mammalian-phenotype-requests]
Betreff: [obo:mammalian-phenotype-requests] #1414 increased urinary mineral level synonyms
HPO has a term called Renal Potassium wasting (undefined). So we may want to make the synonym renal X wasting
[mammalian-phenotype-requests:#1414]http://sourceforge.net/p/obo/mammalian-phenotype-requests/1414/ increased urinary mineral level synonyms
Status: open
Labels: new synonym request
Created: Wed Oct 02, 2013 08:32 PM UTC by Sue Bello
Last Updated: Wed Oct 02, 2013 08:32 PM UTC
Owner: nobody
Consider adding the synonym X wasting for the terms
increased urine calcium level (i.e. calcium wasting)
increased urine magnesium level
increased urine potassium level
See J:159706 for calcium and magnesium
See OMIM (241200 and others) for potassium also http://www.nlm.nih.gov/medlineplus/ency/article/000308.htm Medline Plus article
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Mammalian Phenotype Requests: #1414