I am having the same problem here. I'm using BLAST 2.10.1 and CDHIT 4.8.1, and i got the following segmentation error: [18:46:17] searching related sequences... [18:46:41] clustering subject sequences... /picb/evolgen/users/gushanshan/software/provean/installed/bin/provean.sh: line 188: 51582 Segmentation fault $COMMAND Could you give me some tips? Best regards,