Indels at protein level
Hi Ingrid, Yes I'd move it to the other tracker (well the new tracker - https://github.com/geneontology/go-ontology/issues...
PTN000186208 mapping to GO:0005663
Ingrid, I am surprised that you think the taxon constraints should have caught this,...
PTN000007197 mapping to GO:0043231
Hi Ingrid, I fixed the family. Next time can you give the the accession of the protein...
I think collapsing the process/function distinction here would be a good move. The...
Yes these definitions are good, thanks ! I agree the ATP/ADP-activated was confusing....
Hi David, Sorry I missed that you had renamed the terms: GO:0045031 ATP-activated...
Hi David, I dont understand the TPR then. If a protein is an ATP receptor, it's not...
OK, thanks !
Hi David, There is something odd in the tree: GO:0001609 G-protein coupled adenosine...
Hi Jim, Thanks for the caffeinated comments ! Maybe that was implied, but : One last...
Peter, Just so I am clear: are you saying there is no need to annotate manually to...
Question about F-P link from GO:0016532 superoxide dismutase copper chaperone activity
Question about F-P GO:0045031 (ATP-activated nucleotide receptor activity)
Hi Chris, I also agree that metabolic process is high level but of course everything...
Hi Chris, Having "any process that regulates the acidity of a lysosome lumen occurs...
Hi Chris, I am not sure I understand what your comments imply. One issue is that...
Incorrect inter-ontology link ?
Hi Val, David, The comment is useful, I'm in favor of adding something like that....
NTR intracellular G-protein coupled receptor activity
I agree. Col 16 materials.
Ah thanks ! I need to check the annotations then - is seems unlikely the same proteins...
MP GO:0004660 protein farnesyltransferase activity ?
Query on GO:0023014 signal transduction by phosphorylation
Missing parent ? protein ubiquitination involved in ubiquitin-dependent protein catabolic process
ok, thanks !
Missing parent ? protein ubiquitination involved in ubiquitin-dependent protein catabolic process
Missing parent ? protein ubiquitination involved in ubiquitin-dependent protein catabolic process
IPR006534 mapped to GO:0006200 obsolete ATP catabolic process
IPR006534 mapped to GO:0006200 obsolete ATP catabolic process
Parent GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
Missing aprent S-methyl-5-thioadenosine phosphorylase activity?
(If there are no more comments, this issue can be closed. I'll leave it open for...
Hi Paul, Rama, I reviewed the annotations, trying to implement Paul's suggestions....
Hi Paul, According to http://dehydrogenase.co.uk/ I think these proteins are dehydrogenases...
... same for mitosis/mitotic nuclear division
GO:0007126 meiosis merged with meiotic nuclear division?
sure, but here you are talking about 'regulation of'. Shouldn't regulation be outise...
My understanding was that none of this was 'metabolism'. Or else all cellular processes...
GO:0000084 mitotic S phase
OK, thanks !
Hi Val, To be consistent with https://sourceforge.net/p/geneontology/ontology-requests/11253/...
GO:0000084 mitotic S phase
Ah ok, thanks! I think I have asked before. It always throws me off that we dont...
Parent GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
PTN001593502 mapping to chromatin
PTHR000006656 and 6657
PANTHER:PTN000120057
Review PTHR11309
Fixed by Huaiyu Oct 31, 2014
PANTHER:PTN000120057
PTN001593502 mapping to chromatin
Hi Ingrid, Thanks for the feedback. I removed the annotations referring to chromatin...
Hello, I know I brought that up before - but just to be sure we're aware that the...
I agree with Val - this doesn't seem to be catabolism. Pascale
Good point Val ! I agree they should merge. My favorite term name is 'ubiquitinyl...
NADPH-adrenodoxin reductase activity - wrong EC link
PANTHER:PTN000156122 SERPIN ANNOTATION
Hi Helen, I am finally having a look at this one. Looks like you guys have made the...
mp GO:0006261 DNA-dependent DNA replication
GO:0004221 ubiquitin thiolesterase activity should be deleted, see http://sourceforge.net/p/geneontology/ontology-requests/11094/...
Hello Paul, Looking at the two papers (PMID_ 21855797, PMID_ 25215947), my opinion...
Hi David, I really do think these terms should be obsoleted, both cytochrome c and...
Hi David, I thought we had decided not to create x protein biosynthetic process....
I have fixed the offending family. I know we have other taxon constraints violations,...
Hi Karen, "Protein aggregate" sounds a like an artifact; if that solution is chosen,...
Val is right - the definition of "catabolic process" needs to be made narrower. Thanks,...
Hi Jim, This is a family that was curated a long time ago, before the taxon constraints...
Hi Chris, That sounds like a sensible solution. Thanks, Pascale
This is probably beyond my intellectual capacities...... but why is cell a cell component...
query lactation
Hi Paola, Thanks for looking into this. I still think the definition for axon development...
Thanks Paola, I didn't mean to link to 'regulation of appetite'; I meant to do the...
Ho Paola, That would work. The parents of'GO:0002023 reduction of food intake in...
Question: difference between axon development and axonogenesis
Is GO:0002023 reduction of food intake in response to dietary excess a phenotype ?
Hi Val, I think that's right, see also http://en.wikipedia.org/wiki/Telomere "During...
Hi David, That seems like a good solution - as far as I can tell, the type of proteins...
Should "protein peptidyl-prolyl isomerization" have some link to "protein folding" ?
... but I think those are repaired by the NER pathway... see http://en.wikipedia.org/wiki/Pyrimidine_dimer...
Hello, UV does not just cause one type of damage: " UV radiation induces a much wider...
OTR GO:0000160 phosphorelay signal transduction system
Hi David, I am not sure I am following what you are saying: I think GO:0004221 has...
Obsolete or merge 'ubiquitin thiolesterase activity'
OTR: oncostatin-M receptor complex
Yes, thanks !
Is "neutrophil mediated immunity" an "immune response" ?
OTR: oncostatin-M receptor complex
NTR: regulation of transcription involved in carbohydrate catabolism
Apelin is a gene product
Hi David, Thanks for the explanations. If that term should not be used for annotation,...
Hi David, That doesn't help clear the confusion - this just shows that MP is a process....
It still seems like a process to me. Why not just use "GO:0004871 signal transducer...
Is this a MF ? " GO:0005057 receptor signaling protein activity"?
Hello, According to wikipedia, Chemotropism can occur in single-celled organisms,...
Hi Val, Good point. However I propagated this because it was annotated across multiple...
Hi Ruth, I was talking about dimerization as a MF versus dimer as CC. I dont see...
OK, thanks !