Activity for Paul Denny
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Paul Denny posted a comment on ticket #11812
Dear David, I like your revised def. "The directed movement of a protein to the mitochondrion...
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OK - thanks, David
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NTR- phosphatidylinositol-5-phosphate biosynthetic process
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Definition of GO:0072655 establishment of protein localization to mitochondrion?
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protein localization and transport ontology relationship problem(s)?
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Interesting - thanks Marc. This protein is encoded by a Parkinson's disease risk...
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New term request - placeholder - “mitochondrion degradation”
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Recent review found after second meeting (19th May) PMID: 25009776 Discusses three...
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Please include dbxref GOC:PARL
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Great, thanks!
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At the Warwick Autophagy meeting, these processes were mentioned - should we contemplate...
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adding GOC xref for Parkinson's UK funded project GOC:PARL to term
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NTR - child to mitophagy and also grandchild
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FYI - no-one talked about "autophagic vacuole" at a recent UK Autophagy meeting (https://www.regonline.co.uk/builder/site/default.aspx?EventID=1656031)...
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I see what you mean about auto=self and so virophagy doesn't really fit. I don't...
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Hi David any news? Cheers, Paul
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thanks, David Paul
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NB please use GOC:pad GOC:PARL Thanks!
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Other term-related request - incorrect synonym of GO:0006914 autophagy
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add synonym for GO:0071211 protein targeting to vacuole involved in autophagy
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Hi Tanya, just this one, thanks.
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adding GOC:xref to terms created previously by Birgit Meldal at EBI
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Thanks David!
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NTR: Selective viral autophagy (virophagy) promotes survival of virus infected cells
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Hi David This may need a separate SF ticket, but I think there is also a need for...
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My apologies - I had created this request already under #11296
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new term request; chaperone mediated autophagy (CMA)
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Dear David, Val, thanks very much for your help - these sound good to me. Paul
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Thanks Val, David. Agreed about GO:0043653 mitochondrial fragmentation involved in...
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either child term or synonym request for GO:0000266 mitochondrial fission
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new term request - PINK1-PARKIN dependent mitophagy pathway
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NB Should be relatively easy to sort this out
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New relationship? - GO:0007005 mitochondrion organization parent of GO:0000422 mitochondrion degradation?
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Hi Paola happy with feedback from Val and Pascale and I was already using a child...
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Another thought on this CC term request - mitochondria become depolarised prior to...
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In response to Paola, mitophagy is observed in absence of external inducers, but...
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NTR - response to depolarised mitochondrion
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No worries, thanks. Paul
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Hi david - how is tidying up / merging of these progressing? Cheers
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HI David - how is this NTR progressing? Cheers
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thanks for explanation!
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term GO:0016303 1-phosphatidylinositol-3-kinase activity synonym query
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Hi David, The outcome of the normal BP, GO:0051882 mitochondrial depolarisation,...
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specificity is not just to KFERQ motif, but to KFERQ-related motifs.
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NTR - chaperone mediated autophagy (CMA) as child to autophagy
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NTR child to Positive regulation of glutamate secretion, neurotransmission
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HI David, I tried looking at the contents of the links: synchronous neurotransmitter...
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Sorry, meant this: "reserve pool of synaptic vesicles"
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Thanks Paola - look good, but please would you add an EXACT synonym to id: GO:1990476...
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11100 NTR: Synaptic Vesicle Pools Hi Paola thanks for this - I think part_of GO:0043195...
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NTR: children to GO:0007269 neurotransmitter secretion
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NTR: Synaptic Vesicle Pools
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Thx for adding this - Protein2GO doesn't recognise somatodendritic compartment ;...
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NTR - GO:0048791 calcium ion-dependent exocytosis of neurotransmitter - child
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adding GOC:xref to terms created previously
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changing my personal GOC:xref
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Thanks David - will try term genie
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late endosome to lysosome transport
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Thanks Paola, I don't think this should be a child term of GO:0030175 filopodium...
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dendritic filopodium - child to GO:0030425 dendrite
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