Hi,
Please could I request the following new terms for annotation of rat EGR1 from PMID 8910451
as children of glomerulus development GO:0032835
--<Glomerular mesangium development GO:NEW [Defn: The progression of the glomerular mesangium over time from its initial formation until its mature state. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus].
--<Glomerular mesangium cell proliferation GO:NEW [Defn: The multiplication or reproduction of glomerular mesangium cells by cell division, resulting in the expansion of their population. Mesangial cells are myofibroblasts phenotypically related to vascular smooth muscle cells, which make up the composition of the glomerular mesangium]
Thanks,
Yasmin.
Hi,
Just to expand this a little:
for the term
--<Glomerular mesangium cell proliferation GO:NEW
will need children:
--< Extraglomerular mesangial cell proliferation GO:NEW [Defn: The
multiplication or reproduction of extraglomerular glomerular mesangium cells by cell
division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa].
--< Intraglomerular mesangial cell proliferation GO:NEW [Defn: The
multiplication or reproduction of intraglomerular glomerular mesangium cells by cell
division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis].
Hi,
I will also need the following for annotation of (recombinant) human BMP4 and 7 in PMID:17244894:
--<Glomerular mesangium/mesangial cell proliferation GO:NEW
--<regulation of glomerular mesangium/mesangial cell proliferation GO:NEW
--<positive regulation of glomerular mesangium/mesangial cell proliferation GO:NEW
--<negative regulation of glomerular mesangium/mesangial cell proliferation GO:NEW
thanks,
Yasmin
added
glomerular mesangium development GO:0072109
glomerular mesangial cell proliferation GO:0072110
cell proliferation involved in kidney development GO:0072111
extraglomerular mesangial cell proliferation GO:0072122
intraglomerular mesangial cell proliferation GO:0072123
regulation of glomerular mesangial cell proliferation GO:0072124
negative regulation of glomerular mesangial cell proliferation GO:0072125
positive regulation of glomerular mesangial cell proliferation GO:0072126