Best Zero Trust Security Software for Microsoft 365

Compare the Top Zero Trust Security Software that integrates with Microsoft 365 as of November 2025

This a list of Zero Trust Security software that integrates with Microsoft 365. Use the filters on the left to add additional filters for products that have integrations with Microsoft 365. View the products that work with Microsoft 365 in the table below.

What is Zero Trust Security Software for Microsoft 365?

Zero trust security software, also known as zero trust networking software, provides a security solution based on the zero trust methodology. Zero trust security solutions enable organizations to enforce security policies on a "zero trust" basis for both internal and external users, and allow security teams to track, monitor, and analyze user behavior and usage across the network to identify potential threats. Compare and read user reviews of the best Zero Trust Security software for Microsoft 365 currently available using the table below. This list is updated regularly.

  • 1
    Auth0

    Auth0

    Okta

    Auth0 takes a modern approach to Identity, providing secure access to any application, for any user. Safeguarding billions of login transactions each month, Auth0 delivers convenience, privacy, and security so customers can focus on innovation. Auth0 is part of Okta, The World’s Identity Company™. Auth0 lets you quickly integrate authentication and authorization for web, mobile, and legacy applications, with new Fine Grained Authorization (FGA) that goes beyond role-based access control. Authenticate users across all applications with a customized, secure, and standards-based single login. Universal Login connects users to a central authorization server. Credentials aren’t transferred across sources, which boosts security and protects against phishing and credential stuffing attacks. OAuth 2.0 recommends that only external user agents (like the browser) be used by native applications for authentication flows. Auth0’s Universal Login achieves this while enabling SSO.
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    Starting Price: Free plan
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  • 2
    Keeper Security

    Keeper Security

    Keeper Security

    Keeper Security is transforming the way people and organizations around the world secure their passwords and passkeys, secrets and confidential information. Keeper’s easy-to-use cybersecurity platform is built on a foundation of zero-trust and zero-knowledge security to protect every user on every device. Keeper’s solution deploys in minutes and seamlessly integrates with any tech stack to prevent breaches, reduce help desk costs and ensure compliance. Trusted by millions of individuals and thousands of organizations globally, Keeper is the leader for best-in-class password and passkey management, secrets management, privileged access, secure remote access and encrypted messaging. Protect what matters at KeeperSecurity.com.
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    Starting Price: $2.00 per user, per month
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  • 3
    ManageEngine ADSelfService Plus
    ADSelfService Plus is an on-premises access management solution that caters to businesses across various industries, such as IT, banking, engineering, education, aviation, and telecommunications. Key features include: 1. Self-service password resets and account unlocks: Users can reset their passwords in AD and unlock their domain accounts from a web browser. 2. MFA: Machine logins, VPN and OWA logins, and cloud app logins can be secured using MFA. 3. Password synchronizer and SSO: Users can log in to multiple apps using one unified identity via SSO and real-time password synchronization. 4. Password policy enforcer: Admins can configure custom password policies to enforce strong password creation. 5. Password expiration notifier: Admins can send end users password expiration notifications via SMS or email. 6. Directory self-update: Users can update their AD attribute information through the directory self-update feature.
    Starting Price: $595 for 500 domain users/year
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  • 4
    Cipherise

    Cipherise

    Cipherise

    With over 5000 SAML integrations, experience seamless and secure connections with Cipherise - the platform that offers infinite ways to connect with your employees and customers. By integrating with Cipherise, you can easily build authentication into any app, and offload customer identity management to create delightful experiences quickly. With Cipherise's mutual, bi-directional authentication, you get the security, scalability, reliability, and flexibility to build the stack you need. You will know the person who registered continues to be that person, and they know you are you. Plus, you can protect and enable your employees, contractors, and partners with Cipherise enterprise solutions - no matter where they are. One of the key features, that separate Cipherise from all others - Cipherise eliminates Mass Data Breaches. An attack is limited to one user on one system. Additionally, we store no passwords. Cipherise streamlines your identity and access management needs.
    Starting Price: $30 per user per month
  • 5
    FileFlex

    FileFlex

    FileFlex

    The FileFlex Enterprise ZTDA platform provides secure remote data access and sharing across your entire Hybrid-IT infrastructure to protect your most valuable asset, your corporate data. The FileFlex Enterprise patented Zero Trust Data Access (ZTDA) architecture uses innovative, granular file and folder level micro-segmentation to greatly reduce an attacker’s ability to move laterally within your organization. FileFlex Enterprise authenticates and authorizes every transaction needing remote access to your data without allowing access to your network infrastructure, all without a VPN. Remote access and share to on-premises storage on servers, server-attached, network-attached, FTP and PC storage. IT fully controls all permissions over all users and storage locations even to file level granularity. IT can view and manage all activities of all users down to folder level.
    Starting Price: $9.95 per user per month
  • 6
    CyberArk Workforce Identity
    Empower your workforce with simple and secure access to business resources with CyberArk Workforce Identity. Your users need quick access to a variety of business resources. You need confidence it’s them knocking – not an attacker. With CyberArk Workforce Identity, you can empower your workforce while keeping threats out. Clear the path for your team to propel your business to new heights. Validate identities with strong AI-powered, risk aware and password-free authentication. Streamline management of application access requests, creation of app accounts, and termination of access. Keep workers working, not logging in and out. Make intelligent access decisions based on AI-powered analytics. Enable access across any device, anywhere at just the right time.
  • 7
    Skyhigh Security Security Service Edge (SSE)
    Skyhigh Security Security Service Edge (SSE) is the security fabric that delivers data and threat protection to any location so you can enable fast and secure direct-to-internet access for your distributed workforce. This results in a transformation to a cloud-delivered Secure Access Service Edge (SASE) that converges connectivity and security to reduce cost and complexity while increasing the speed and agility of your workforce. Skyhigh Security Security Service Edge (SSE) delivers fast and secure SASE via its always-on Hyperscale Service Edge and integration with industry leading SD-WAN solutions. Skyhigh Security Security Service Edge's unified approach to data protection provides complete visibility and control from device to cloud. Enable unified data protection policies and incident management without increasing overhead.
  • 8
    Symantec Integrated Cyber Defense
    The Symantec Integrated Cyber Defense (ICD) Platform delivers Endpoint Security, Identity Security, Information Security, and Network Security across on-premises and cloud infrastructures to provide the most complete and effective asset protection in the industry. Symantec is the first and only company to unify and coordinate security. Functions across both cloud and on-premises systems. Symantec enables enterprises to embrace the cloud as it makes sense for them, without sacrificing past investments and reliance on critical infrastructure. We know Symantec will never be your only vendor. That’s why we created Integrated Cyber Defense Exchange (ICDx), which makes it easy to integrate third-party products and share intelligence across the platform. Symantec is the only major cyber defense vendor that builds solutions to support all infrastructures, whether entirely on-premises, entirely in the cloud, or a hybrid of the two.
  • 9
    Symantec Secure Access Service Edge (SASE)
    SASE is a vision of converged technologies to improve network performance and security for users who can be anywhere, use any device, and need access to content and applications from corporate data centers and cloud platforms. Symantec can help you achieve all of the benefits of digital transformation and SASE through low-latency cloud and internet access, as well as a complete range of integrated best-in-class network security capabilities. Get advanced, cloud-delivered network security service to enforce consistent web and cloud application security and compliance policies for all users, regardless of location and device. Prevent loss of sensitive data and exfiltration of intellectual property at the service edge. Protect your applications and resources from unauthorized access, network-based attacks, and lateral movement with Zero Trust Network Access (ZTNA) technology.
  • 10
    iboss

    iboss

    iboss

    iboss is a cloud security company that enables organizations to reduce cyber risk by delivering a Zero Trust Secure Access Service Edge platform designed to protect resources and users in the modern distributed world. Applications, data, and services have moved to the cloud and are located everywhere, while users needing access to those resources are working from anywhere. The iboss platform replaces legacy VPN, Proxies, and VDI with a consolidated service that improves security, increases the end-user experience, consolidates technology, and substantially reduces costs. Built on a containerized cloud architecture, iboss delivers security capabilities such as SWG, malware defense, Browser Isolation, CASB, and Data Loss Prevention to protect all resources via the cloud instantaneously and at scale. The iboss platform includes ZTNA to replace legacy VPN, Security Service Edge to replace legacy Proxies, and Browser Isolation to replace legacy VDI. This shifts the focus from protecting
  • 11
    Sangfor Athena SASE

    Sangfor Athena SASE

    Sangfor Technologies

    Sangfor Athena SASE is a cloud-native Secure Access Service Edge platform that combines advanced security features with wide-area network agility. It provides seamless, secure access to cloud resources, on-premises applications, and the internet for today’s distributed and hybrid workforce. The platform integrates Zero Trust Network Access (ZTNA), Secure Web Gateway (SWG), Firewall as a Service (FWaaS), Data Loss Prevention (DLP), and Endpoint Detection and Response (EDR) into a unified solution. Athena SASE simplifies network and security management through a single, centralized console, reducing complexity and operational overhead. Its global architecture supports fast, reliable connectivity anywhere, enabling smooth geographic expansion and regulatory compliance. This platform empowers organizations to secure hybrid work environments while optimizing performance and cost.
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    SecureW2

    SecureW2

    SecureW2

    Even for organizations under 500 employees, a 2020 IBM report found credential compromise averaged $2.35M in costs. Eliminate the threat by using x.509 certificates for Wi-Fi, VPN, Web Apps, Endpoint Login & more. Leverage your existing Wi-Fi, Web, Firewall and VPN infrastructure with zero technology forklift upgrades. With SecureW2, you can verify that only trusted users and devices can access your network and applications. Enabling 802.1x in the cloud has never been easier. SecureW2 provides everything you need to use your Azure, Okta, or Google to enroll and manage certificates for secure Wi-Fi authentication. Plus it comes with the World’s only Dynamic Cloud RADIUS server, giving you everything you need for secure WPA2-Enterprise network authentication. Onboard every major operating system with ease and deliver secure connections with no IT burden. Secure your network with certificates using the generation, delivery, authentication and renewal technology.
  • 13
    Check Point Infinity
    Organizations frequently implement multiple cyber security solutions in pursuit of better protections. As a result, they are frequently left with a patchwork security architecture that results in a high TCO. By adopting a consolidated security approach with Check Point Infinity architecture, businesses realize preemptive protection against advanced fifth-generation attacks, while achieving a 50% increase in operational efficiency and 20% reduction in security costs. The first consolidated security architecture across networks, cloud, mobile and IoT, providing the highest level of threat prevention against both known and unknown cyber-threats. 64 different threat prevention engines blocking against known and unknown threats, powered by threat intelligence. Infinity-Vision is the unified management platform for Check Point Infinity, the first modern, consolidated cyber security architecture built to prevent today’s most sophisticated attacks across networks, cloud, endpoints, etc.
  • 14
    Acceptto Zero Trust Identity (CIAM)
    You need to know that your customers are who they say they are, customers don’t want to jump through hoops to prove it and they want you to keep their credentials safe. Protect your customers identities through a delicate balance of security and a frictionless, pleasant customer experience. Real-time, continuous identity monitoring & validation Post-Authorization. Eliminate account takeover (ATO) instantly with intelligent MFA. Risk-based policy orchestrated continuous authentication. Acceptto is a transformative cybersecurity company driving a paradigm shift in identity access management by treating authentication not as a single event, but rather a continuum. Our AI/ML powered Passwordless Continuous AuthenticationTM technology analyzes and verifies user identity, inferring behavioral data to detect anomalies and eliminate dependence on vulnerable binary authentications. We deliver the smartest, most resilient and breach-proof identity validation technology.
  • 15
    VeloCloud SASE
    VeloCloud SASE, secured by Symantec, is a next-generation secure access service edge (SASE) solution that combines software-defined wide area networking (SD-WAN) with robust security features to protect enterprise networks. It offers a cloud-delivered architecture that enables businesses to securely connect their branch offices, remote workers, and cloud applications while maintaining high performance. The platform provides integrated security functionalities such as secure web gateways, cloud firewall, and threat intelligence, helping businesses ensure secure, efficient access to their applications across distributed networks.
  • 16
    Resec

    Resec

    Resec

    With over 300 billion emails sent per day, targeting organizations via email has become a favorite for hackers. Resec for Email provides superior protection from advanced threats coming from both on-premise and cloud-based mail services. Our solution enables users to open emails and attachments safely, freely, and without unnecessary latency. Encrypted attachments are fully supported, increasing security and reducing falsely blocked emails and IT overhead. Every email is treated as a potential threat. Resec provides full prevention of known and unknown malware attacks before they enter your organization. No agents or client-based footprint. Customizable according to group-level policies. Low overhead on IT staff and easy to maintain. Superior advanced protection from malware and ransomware attacks arriving from emails and attachments.
  • 17
    SecHard

    SecHard

    SecHard

    SecHard is a multi-module software for implementing zero-trust architecture. SecHard provides automated security hardening auditing, scoring, and remediation for servers, clients, network devices, applications, databases, and more. A powerful identity and access management software to get compliant with zero trust and to prevent attacks like privilege abuse, ransomware, and more. SecHard solves the risk awareness problem in asset management. Automated discovery, access, identification, and remediation features provide ultra-wide visibility for all regulations. With the passive scanning method, SecHard operates the vulnerability detection and management processes for all IT assets without creating any risks. SecHard auto-discovers the certificates in the company’s environment report the expiration dates of these certificates, and it can automatically renew some of these certificates through well-known certificate authorities.
  • 18
    Fortinet Universal ZTNA
    Fortinet Universal ZTNA provides secure and simple access to applications, regardless of where they are located, for users working from anywhere. As the hybrid workforce becomes the new normal, employees must be able to securely access all of their work applications from multiple locations. Fortinet Universal ZTNA ensures secure access to applications hosted anywhere, whether users are working remotely or in the office. Zero Trust is all about trusting users and devices only after they have been verified. Watch the video to learn how to achieve simple, automatic secure remote access that verifies who and what is on your network. Fortinet ZTNA secures application access no matter where users are located. Our unique approach, delivering Universal ZTNA as part of our operating system, makes it uniquely scalable and flexible for both cloud-delivered or on-prem deployments, covering users whether they are in the office or remote.
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