Compare the Top USB Security Software for Mac as of June 2025

What is USB Security Software for Mac?

USB security software is a type of application designed to protect against malicious USB attacks. It can help keep your data safe by monitoring your USB ports for any unauthorized activity and preventing the transfer of any potentially dangerous files from unsecured flash drives. This software comes with various levels of protection, such as encryption, anti-malware scans, and real-time alerts. In addition, it can also provide you with an audit trail that tracks all activities associated with your USB ports. Lastly, these applications are simple to install and use yet can be highly effective in keeping your data secure against malicious attacks. Compare and read user reviews of the best USB Security software for Mac currently available using the table below. This list is updated regularly.

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    ThreatLocker

    ThreatLocker

    ThreatLocker

    The ThreatLocker suite of security tools are powerful and designed so that everyone from businesses to government agencies to academic institutions can directly control exactly what applications run on their networks. We envision a future in which all organizations can chart their own course free from the influence of cybercriminals and the damage their incursions cause, and our team of veteran cybersecurity professionals created ThreatLocker to make this vision a reality. The team at ThreatLocker has been developing cybersecurity tools for decades, including programs to enhance email and content security, and this is our most innovative and ambitious cybersecurity solution yet. We developed this unique cybersecurity system because we believe that organizations should have complete control of their networks and should not have to live in fear of the next malware attack. To learn more, visit ThreatLocker.com.
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  • 2
    Safetica

    Safetica

    Safetica

    Safetica Intelligent Data Security protects sensitive enterprise data wherever your team uses it. With advanced data discovery, context-aware classification, proactive threat prevention and adaptive security, Safetica provides comprehensive visibility and control over your data. ✔️ Discover what to protect: Precisely locate personally identifiable information, intellectual property, financials, and more wherever it is used across the enterprise, cloud, and endpoint devices.  ✔️ Prevent threats: Understand and mitigate risky behavior with ​automatic detection of suspicious file access, email ​communication and web browsing. Get the ​alerts you need to proactively uncover risk and ​prevent data breaches.  ✔️ Keep your data safe: Intercept unauthorized exposure of sensitive personal ​data, trade secrets and intellectual property. ​  ✔️ Work smarter: Help teams work, with in-moment data handling cues ​as they access and share sensitive information. 
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  • 3
    Bitdefender GravityZone
    Bitdefender GravityZone provides full visibility into organizations' overall security posture, global security threats, and control over its security services that protect virtual or physical desktops, servers and mobile devices. All Bitdefender's Enterprise Security solutions are managed within the GravityZone through a single console, Control Center, that provides control, reporting, and alerting services for various roles within the organization
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    Donglify

    Donglify

    Donglify

    Donglify solves the dongle-sharing problem. The app allows you to use a USB dongle even when you don't have it at hand. You can redirect your licensed USB dongles to any location over the network. It’s not uncommon that an owner of a licensed USB key needs to access the functionality of their device when a physical connection to the device is not possible. Donglify helps resolve this problem once and for all. Thanks to the advanced port redirection technology that powers the solution, you can forward your USB security dongles over any distance and to any environment. If a USB dongle that’s attached to your computer is not recognized by the virtual machine you are running, no worries. Just install Donglify on both the host and guest operating systems and redirect your device to a virtual environment without any limitations. Create login tokens and send them to other Donglify users.
    Starting Price: $16 per month
  • 5
    Endpoint Protector
    Endpoint Protector is an advanced, all-in-one Data Loss Prevention solution for Windows, macOS and Linux, that puts an end to data leaks and data theft and offers seamless control of portable storage devices. Endpoint Protector’s filtering capabilities for data at rest and in motion range from file type to predefined content based on dictionaries, regular expressions or data protection regulations such as GDPR, PCI DSS, CCPA, HIPAA, etc. Endpoint Protector features several specialized modules that can be mixed and matched based on client needs. The modules comprise: Content Aware Protection, Device Control, Enforced Encryption, and eDiscovery . It makes work more convenient, secure and enjoyable, offering an excellent ROI.
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    USB Block

    USB Block

    NewSoftwares

    Prevent data leaks by restricting USB drives, external devices, network computers, and ports on your PC. Whitelist your own portable drives and block all others. USB Block prevents data leaks through devices like USB drives, phones, tablets, and other devices that are attached to your PC. It even prevents certain ports and partitions from accessing. You can whitelist trusted devices. This way you can copy data to your own USB, External drives, your iPhone or Android phone but block other such devices from accessing your PC. This feature helps you check whether someone has tried to hack into USB Block by using incorrect passwords All incorrect passwords will be logged to monitor any suspicious activity. Lock and password protect your data from unwanted access and visibility by blocking access to the files, folders, drives, and programs. Windows kernel-level locking and filter driver makes it possible to lock files and folders in Windows.
    Starting Price: Free
  • 7
    DriveSecurity

    DriveSecurity

    DriveSecurity

    DriveSecurity® (by ClevX®) is a powerful antivirus tool that prevents malware from spreading through USB drives. Designed for users who transfer pictures, music, videos and other documents via USB drives, DriveSecurity ensures the files that you put on your drive are malware-free. DriveSecurity eliminates all types of threats, including viruses, rootkits, worms and spyware from your USB drive. More importantly, it protects you from inadvertently spreading malware to your home or shared computers.
    Starting Price: $ 0.71 per month
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