Compare the Top On-Premises Standard Operating Procedure (SOP) Software as of November 2025

What is On-Premises Standard Operating Procedure (SOP) Software?

Standard operating procedure (SOP) software allows companies to optimize their efficiency through the management of documents, employee training, and regulation compliance. Compare and read user reviews of the best On-Premises Standard Operating Procedure (SOP) software currently available using the table below. This list is updated regularly.

  • 1
    Process Street

    Process Street

    Process Street

    Process Street is an AI-powered compliance operations platform that automates complex workflows, enforces standards, and tracks audit data in real time. Teams use it to create structured SOPs, assign tasks, collect data, and monitor execution with intelligent oversight. From onboarding and audits to vendor management and document control, Process Street ensures every step is followed and every action is logged. Built for regulated industries like financial services, healthcare, and manufacturing, it supports frameworks such as ISO, SOC 2, SOX, and HIPAA. With role-based permissions, audit logs, and powerful integrations, Process Street replaces static documents, spreadsheets, and manual processes with a single automated system of record. Use AI to streamline approvals, catch risks early, and generate audit-ready evidence. Trusted by teams at Cargill, DoorDash, Farmers Insurance, and Hartford Healthcare.
    Starting Price: $1500/month
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  • 2
    Epsilon3

    Epsilon3

    Epsilon3

    Epsilon3 is an AI-powered procedure and resource management tool designed for teams building, testing, and operating advanced products and systems. ✔ Standardize & Optimize Processes Our interoperable procedure execution system replaces inefficient checklists managed with paper, spreadsheets, docs, and outdated planning tools. Automatically track every step to ensure quality, consistency, and traceability. ✔ Fuel Rapid Iteration & Innovation Built-in version control, conditional workflows, and real-time data synchronization keep teams on the same page. Enable continuous improvement and quick, data-driven decisions to stay far ahead of the competition. ✔ Streamline & Scale Operations Securely integrate siloed systems and automate error-prone tasks to boost productivity and prevent delays. Simplify training, reduce costs, and maintain efficiency as your operations expand to meet demand. Trusted by industry leaders like NASA, Firefly Aerospace, and Commonwealth Fusion.
    Starting Price: $100/user/month
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  • 3
    Interfacing Enterprise Process Center (EPC)
    Interfacing’s Digital Twin Organization software provides transparency and Governance to improve Quality, Efficiency, and ensure Regulatory Compliance. Map, analyze, and automate processes, manage regulatory compliance, assess risks within a single platform! Interfacing’s digital twin solution (Enterprise Process Center - EPC) is an enterprise management system that helps companies digitalize processes to streamline operations, increase productivity, and continuously improve. Interfacing’s digital business platform – Rapid Application Development (RAD) Tools, with its Low-Code Development methodology will optimize usage of your technical resources and maximize transparency for ongoing improvement. Discover how our Low-Code Rapid Application Development module provides all the tools to create and deploy Custom, Scalable, Secure, and Mobile ready Applications in Days vs. Months!
    Starting Price: $10/month/user
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  • 4
    Opus●Guide

    Opus●Guide

    Opus●Guide

    Opus●Guide is a tool to systematize your business. Create and manage processes, SOPs, onboarding, training, and knowledge. Chrome extension to generate documents fast, Follow your usual process, just click on buttons. Captures automatically and your process instruction is generated. Finalize your process instruction, and assign roles for easy access to an organization. Systematize your business seamlessly. With our extension, you can quickly capture your screen and create beautiful instructions with screenshots. Create step-by-step instructions in seconds. Capture screenshots, just by clicking on buttons. With Opus●Guide you can create step-by-step instructions in seconds. Click "start" in the extension to automatically capture screenshots and highlight the pointer while you do your process. Edit your newly created instruction.
    Starting Price: $6/month
  • 5
    VKS

    VKS

    Visual Knowledge Share

    VKS is a digital work instruction software that makes it easy for companies to throw out paper work instructions and transform into a digital factory. Create digital work instructions and standard operating procedures (SOPs) using pictures, videos, PDFs, annotations and more. Integrate in-process quality checklists to help reduce defects by up to 95%. Standardize best practices and increase productivity by 20%. With real-time process control and built-in reports, you also get 100% guaranteed traceability. By switching to digital work instructions, you can capture tribal knowledge and eliminate the skills gap. You also benefit from increased communication on the shop floor and the subsequent improved accuracy of your operational decision-making.
  • 6
    CAQ.Net

    CAQ.Net

    CAQ AG Factory Systems

    CAQ AG Factory Systems has established itself as one of the worldwide leading providers of quality management software. We have over 30 years of experience in the development and distribution of modular, multilingual, and industry-specific management solutions for small and medium-sized enterprises as well as multinational corporations. Our CAQ.Net software suite covers every aspect of computer aided quality assurance and was designed with the highest degrees of adaptability and customizability in mind. Just like a construction kit, our system allows you to pick the most suitable building blocks and thereby create the perfect solution to your individual quality management demands. Why CAQ.Net? Updates, Upgrades & Release Changes Support from QM & IT Professionals User Workshops Screencasts Conformity to Standards Information Security SaaS or On-Premises Floating Licenses Multitenancy Multilingual No-Code-Designer Validation Capability AI Assistants ...
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