Best Secure Email Gateway Software for Cloud
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Compare the Top Secure Email Gateway Software for Cloud as of November 2025
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What is Secure Email Gateway Software for Cloud?
Secure email gateways protect organizations from email-based threats such as phishing, malware, spam, and data breaches. They analyze incoming and outgoing messages to detect suspicious content, malicious attachments, and unauthorized data sharing. These gateways enforce email security policies, filter harmful traffic, and provide encryption to safeguard sensitive communications. Many platforms also integrate with cloud email services like Microsoft 365 and Google Workspace to extend protection across hybrid environments. Ultimately, secure email gateways help maintain compliance, protect confidential information, and ensure safe, reliable business communication. Compare and read user reviews of the best Secure Email Gateway software for Cloud currently available using the table below. This list is updated regularly.
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NeoCertified Secure Email
NeoCertified
NeoCertified protects sensitive information through our secure email application across our versatile Cloud-based platform on any web browser, through Microsoft Office 365/Outlook plug-ins, and Gmail integration. iPhone + Android mobile apps are also available directly on your mobile devices. We have provided federally compliant, secure email solutions since 2002, and have helped businesses send and receive secure emails on any web browser or mobile device. NeoCertified also works across all email providers to give businesses the flexibility and assured protection they desire and deserve.Starting Price: $99.00/year/user -
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N-able Mail Assure
N-able
N-able Mail Assure cloud-based email security solution provides advanced threat protection for inbound and outbound email using collective threat intelligence, 24/7 email continuity, and long-term email archiving. The service includes a multitenant web-interface with predefined settings, reporting, and views designed to ensure control and visibility over email flows. N-able Mail Assure’s proprietary technology incorporates input from processing large volumes of email data that feeds the Intelligent Protection and Filtering Engine. This combined with real-time pattern threat recognition leveraging a variety of filtering technologies help protect against spam, viruses, phishing attacks, impersonation, spoofing, malware, and other email-borne threats. -
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Zoho Mail
Zoho
Secure email hosting for your business. Host your business email on a secure, encrypted, privacy-guaranteed, and ad-free email service. Zoho Mail's data centers have top-notch security and surveillance, with a reliable 99.9% uptime. Benefit from secure email hosting that supports encryption both at rest and end-to-end, along with S/MIME message encryption. Create a domain for your business and set up custom email addresses for users. Unique and professional email addresses give your company the visibility and authenticity it deserves. Zoho Mail's powerful Control Panel is the admin's go-to place for all settings, configuration, and customization. Add users, manage group aliases, set up policies to moderate business email content, and more. Retain emails across your organization for a specified period to comply with company standards and to counter legal attacks. e-Discovery helps discover such retained emails quickly.Starting Price: $2.00/month/user -
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Microsoft Exchange
Microsoft
Work smarter with business-class email and calendaring. Exchange helps you collaborate on your critical documents and gives you a focused inbox that prioritizes important messages and adapts to your work style, so you can get more done–faster. Get access to a more personalized inbox with helpful features and a smarter, more organized way to view and interact with email. Search enhancements give you faster and more complete results. With Add-ins, get powerful customization and extensibility, which connect you to modern services and internal line-of-business applications. Organize your time with a calendaring system that goes beyond basic scheduling of appointments and commitments. Automatically capture events from email such as flights and hotel reservations, and get suggestions about where to meet based on your location. Microsoft Exchange Online offers a hosted email service for business. Exchange Online helps protect your information with advanced capabilities. -
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Mimecast Advanced Email Security
Mimecast
Mimecast Advanced Email Security is a robust solution designed to protect organizations from a wide range of email-based threats, including phishing, malware, impersonation attacks, and spam. Leveraging cutting-edge AI and machine learning, Mimecast provides real-time threat detection and prevention to safeguard sensitive information and ensure business continuity. It offers advanced filtering and scanning of incoming and outgoing emails, reducing the risk of data breaches, and helps organizations comply with regulatory requirements. With comprehensive reporting and management tools, Mimecast enables IT teams to efficiently monitor and respond to potential threats, making it a trusted choice for businesses seeking enhanced email security. -
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Proofpoint Email Protection
Proofpoint
Proofpoint Email Protection solutions—deployed as a cloud service or on-premises—protect against malware and threats that don't involve malware, including impostor email, or business email compromise (BEC). Granular email filtering controls spam, bulk "graymail" and another unwanted email. And continuity capabilities keep email communications flowing when your email server fails. Proofpoint Email Protection is the industry-leading email gateway, which can be deployed as a cloud service or on premises. It catches both known and unknown threats that others miss. Powered by NexusAI, our advanced machine learning technology, Email Protection accurately classifies various types of email. And it detects and blocks threats that don’t involve malicious payload, such as impostor email—also known as business email compromise (BEC)—using our Advanced BEC Defense. You can also automatically tag suspicious email to help raise user awareness. And you can track down any email in seconds. -
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Advanced protection to safeguard your inboxes. Email is still the No. 1 threat vector. Expand the scope of your defenses to detect dangerous threats and rapidly respond to and remediate new threats in real time. Identify the malicious techniques used in attacks targeting your organization. Understand the specific business risks and categorize threats to gain insight into the parts of your organization that are most vulnerable to attack. AI-driven threat detection uses multiple detection engines to simultaneously evaluate different portions of an incoming email. These verdict details help ensure accurate threat classification, identify business risk, and promote an appropriate response action. Threats come from numerous sources: phishing, business email compromise, malware, and ransomware. Defend against all of them with industry-leading threat intelligence that empowers you to act quickly.
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SecurityGateway™ for Email Servers
MDaemon Technologies
Developed by MDaemon Technologies, an email industry pioneer, Security Gateway's email threat detection technology has been protecting email servers from viruses, spam, phishing, data loss and other threats for over 20 years. Simply put, companies trust our expertise to help keep email communications safe. We protect all email platforms including Microsoft Exchange, Office 365 and others. Let our team of email security experts take the headache out of managing your company's email security needs. Security Gateway uses the latest email threat detection technology and policy enforcement tools to keep good emails flowing to and from your users. The Security Gateway cloud service can be deployed quickly and easily, allowing you to focus on other important tasks. Watch a short video to learn about some of the Security Gateway features.Starting Price: $1 per user per month -
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Barracuda Email Security Gateway
Barracuda
With the Barracuda Email Security Gateway, protecting against inbound malware, spam, phishing, and Denial of Service attacks ensures that business productivity isn’t impacted by attacks through the email system. Powerful and customizable policies enable further enforcement of detailed requirements that govern inbound email messages. Email is a critical vehicle in today’s business world, therefore a failure of the email server can significantly limit business operations. With the Cloud Protection Layer, bundled free of charge with the Barracuda Email Security Gateway, email is spooled for up to 96 hours, with an option to re-direct traffic to a secondary server. Leverage powerful encryption technology to ensure that sensitive data cannot be viewed by outside parties. Outbound filtering and quarantine capabilities certify that every outbound email complies with corporate DLP policies. -
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Zix Secure Cloud
Zix
Unleash your teams to become more productive, secure, and compliant in a complex, digital world. Establish a modern workplace for better data sharing, collaboration, flexibility, and remote work. Best-in-class email encryption, secure file sharing, and business communications archiving (email, social media, instant messaging). All services backed by 24/7/365 dedicated support from our phenomenal care team to better manage people, technology, and process. Automatic email encryption and data loss prevention offer unparalleled peace of mind for you, your employees and your executives. Prevent malware, ransomware and other advanced threats from compromising your email and your business. Provides secure message retention, making compliance and eDiscovery easier for you and your team. -
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Fortinet
Fortinet
Fortinet is a global leader in cybersecurity solutions, known for its comprehensive and integrated approach to safeguarding digital networks, devices, and applications. Founded in 2000, Fortinet provides a wide range of products and services, including firewalls, endpoint protection, intrusion prevention systems, and secure access solutions. At the core of its offerings is the Fortinet Security Fabric, a unified platform that seamlessly integrates security tools to deliver visibility, automation, and real-time threat intelligence across the entire network. Trusted by businesses, governments, and service providers worldwide, Fortinet emphasizes innovation, scalability, and performance, ensuring robust defense against evolving cyber threats while supporting digital transformation and business continuity. -
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Symantec Email Security.cloud
Broadcom
Safeguard Microsoft Office 365, Google G Suite, and on-premises email with the industry’s most complete email security solution. Insulate users from spear phishing, credential theft and ransomware attacks by using Email Threat Isolation. Prevent insidious email threats such as spear phishing, ransomware, business email compromise and email spam. Stop spear phishing emails with multiple layers of protection, threat isolation, spam filtering, advanced security email analytics, built-in user awareness, education tools, and more. Block the latest ransomware with content defense, sandboxing, and link protection technologies that detect emerging, stealthy, and zero-day attacks. Defeat business email compromise with impersonation protection, sender authentication enforcement and brand protection controls. Protect your brand reputation by using automation to solve the practical issues of enforcing sender authentication (DMARC, DKIM and SPF) with Symantec Email Fraud Protection. -
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SEPPmail
SEPPmail AG
Sending and receiving digitally signed and encrypted emails is easier and more convenient than ever before. Thanks to the Secure E-Mail Gateway from SEPPmail with integrated and patented GINA procedure for spontaneous encryption, SMEs and large companies secure their entire e-mail communication at the highest level, with the least effort and simplest handling for sender and recipient. With its comprehensive Secure Email solution, SEPPmail is setting new standards for secure, GDPR-compliant email communication. As one of the world’s leading email encryption and signature solutions, SEPPmail includes all the features to protect the sending of confidential data via email, guarantee the authenticity of the sender and ensure the confidentiality and integrity of the message. Thanks to its modularity, the secure e-mail gateway solution can be configured according to customer-specific requirements and expanded seamlessly.Starting Price: 4.5 € per user per month -
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Spambrella
Spambrella
Dynamically classify imposter email. Preemptively identify and sandbox suspicious URLs. Leverage big-data analysis to accurately classify bulk mail. All within a single service that connects with Microsoft 365 and Google Workspace. Spambrella’s Email Security and User Awareness Training technology is used by some of the World’s largest and most successful security-conscious companies in a multitude of continents and environments. Delivered on a global scale, Spambrella is ready to unify your email security and user awareness training requirements. Think of us as your outsourced email security team! We have deep technical expertise of all other service providers such as MxLogic, Mimecast, Symantec.cloud and know how to migrate you effortlessly. Schedule a demo today with our cybersecurity experts to uncover email threats targeting your email users.Starting Price: $1.00 -
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LuxSci
Lux Scientiae
LuxSci provides HIPAA-compliant web and email communications services. LuxSci creates uniquely secure and customizable enterprise-grade environments and solutions that enable organizations to confidently meet their specific business and security needs at scale. LuxSci’s HIPAA-compliant email and web solutions are HITRUST certified and include: • Secure High Volume Sending for delivering massive volumes of transactional and marketing emails. • Secure SMTP Connector for encrypting outbound emails sent from Microsoft 365 and Google Workspace. • Secure Email Marketing platform for creating and sending marketing campaigns with ePHI. • Secure Email Hosting for reliable and secure day-to-day business email. • Fully managed Secure Web and Database Hosting for web applications that require compliance. • Secure Forms to safely collect and store sensitive information. LuxSci provides a full suite of secure technology for companies requiring compliant web and email services.Starting Price: $4 per/user/month -
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PhishProtection
DuoCircle
Make your smartest investment to reduce email security threats today, and get a comprehensive email security protection solution with small business pricing. Cybercriminals are targeting CEOs, CFOs, HR, Accounting Departments and regular employees across every industry. As you know Office 365 is extremely limited in the protection that you can configure to stop impersonations, email fraud and phishing. There are only so many custom transport rules you can build to constantly block domains or protect against employee impersonations. PhishProtection works on every email server, device or smtp service. No matter if you are on your phone, or outlook or any email client anywhere, we can protect you. It offers best-in-class security to iOS and Android devices alike.Starting Price: $100/month/user -
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Additional layer of security to stop threats from ever reaching users in the network. Designed to protect email communication, the most vulnerable vector. ESET features a true 64-bit product that allows for clustering to ensure that speed is never a concern for organizations of any size. ESET Mail Security solutions use in-house developed anti-spam, anti-phishing and host server protection, combining machine learning, big data and human expertise into one award-winning mail security platform. Helps eliminate unsolicited emails and targeted attacks, allowing employees to focus on their job and ensure business continuity. Users are constantly targeted via phishing campaigns that may contain other malicious components. A single user will not be efficient due to having to sift through whether emails are legitimate or not. Emails are automatically provided to users about their spam emails that were quarantined.Starting Price: $132 per 5 devices per year
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Secure Exchanges
Secure Exchanges
The easiest secure platform to exchange, retrieve or even sign confidential documents (up to 2.5G of files per email) without compromising sensitive information inside and outside your organization. Our technology offers its users the possibility to add layers of security to their emails exchanges by limiting the number of times they are read, their lifespan or by adding SMS codes or passwords to be sent to their recipients with ease. Because today's online world is a highly vulnerable environment, choose an innovative and secure tool that is unique in the world of computer security. Whether you want to send or receive emails containing large, confidential attachments or documents to be signed. Exchange passwords, credit cards, financial statements, tax returns, incident reports or any information you deem confidential via email. Our technology is there to serve your organization.Starting Price: $0.99 per user per month -
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RMail
RPost
RMail® is the e-security platform by RPost®, a global leader since 2000. RMail specializes in elegantly easy to use email encryption for privacy and compliance, e-signatures, legal e-delivery proof, secure file sharing, email impostor protection, document rights management, and AI-infused services to prevent data leaks and human e-security errors. RMail’s transmission e-security services are most often used by businesspeople or business systems that send important, sensitive, or consumer-regulated information. These RMail services are generally applied to those messages where the sender needs functionality beyond standard email in terms of (a) easier to use and more automated email encryption for privacy compliance, (b) returning a verifiable proof record of who said what to whom by email, (c) assurance and peace of mind related to delivery and open status of important and time-deadline email, (d) need a timestamped proof of content delivered, (f) need to share large files securely.Starting Price: $7/month/user -
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Sophos Email
Sophos
Today’s email threats move fast, and growing businesses need predictive email security – defeating today’s threats with an eye on tomorrow. The same technology as our award-winning Intercept X, Sophos Email sandboxing is a deep learning neural network, able to block zero-day malware and unwanted applications. The most advanced anti-ransomware technology available. Sophos email security uses behavioral analysis to stop never-before-seen ransomware and boot-record attacks. Time-of-click URL protection checks the website reputation of email links before delivery and again when you click – blocking stealthy, delayed attacks that other email security can miss. Processing millions of emails per day, the latest threat intelligence from SophosLabs global network ensures your Sophos Email gateway won’t miss any of the thousands of new threats discovered every hour. -
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Comodo Dome Antispam
Comodo Group
Secure Email Gateway is an enterprise anti-spam and threat prevention system that uses a sophisticated array of spam filters, anti-virus scanners and content analysis engines to prevent unsolicited mail from ever entering your network. Security needs differ from employee to employee. You may want to apply different security levels to different employees such as from finance or sales departments. Dome Anti-spam gives you the freedom to define different types of profiles with different security features and restrictions. Containment protects from the newest forms of ransomware, zero-malware, and other advanced threats. The Valkyrie file verdict system analyzes unknown files. Users are free to open, execute and use the attachments with ZERO risk of infection. Comodo's unique containment technology ensures that risks are fully contained before reaching the end point, so there is no risk of infection, even from the newest malware.Starting Price: $4.00/one-time/user -
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SendSafely
SendSafely
The end-to-end encryption platform for modern business. SendSafely lets you easily exchange encrypted files and information with anyone on any device. Let us take the headache out of secure file exchange. Trusted by leading brands that understand the importance of keeping customer information safe. SendSafely works natively with all major browsers. No software to install, no encryption keys to manage. Use SendSafely for compliance with regulations like HIPAA (BAA available), GDPR, CCPA and more. Use one of our pre-built platform connectors or easily create your own integration with our developer API. Features designed for businesses such as user administration, single sign on and custom branding. SendSafely integrates with many popular third party systems, adding end-to-end encryption to the platforms your users already know and love. Extend the capabilities of your existing apps and infrastructure by seamlessly adding encryption to your existing workflows.Starting Price: $11.50/user/month -
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Ciphermail Appliance
in-put
Email encryption with CipherMail Most emails are sent in plain text. This means that anyone who has access to the data stream can read the content of the emails. This is unacceptable for most companies, institutions and organizations and may also violate applicable law. E-mail encryption ensures security and trust in communication. CipherMail is a central mail transfer agent (MTA) that works on the “store and forward” principle. Incoming e-mails, regardless of whether they are from internal or external sources, are only saved until they have been encrypted / decrypted and can be forwarded to the recipient. This happens without changing the email client and is possible in combination with any SMTP server! E-mail encryption can be done using S / MIME, PGP or in a PDF file - in principle or triggered by a trigger in the subject line. CipherMail also includes a Data Leak Prevention (DLP) module.Starting Price: $670 one-time payment -
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RevBits Email Security
RevBits
RevBits Email Security is a next-generation email security solution that aims to close major gaps in the current marketplace. Leveraging sophisticated and unique algorithms such as a patented page impersonation detection methodology, Revbits Email Security achieves the deepest level of email analysis. For every email, RevBits Email Security displays a composite, probabilistic score of each email's risk level paired with full details for continuing user education. RevBits Email Security enhances Email Security Architecture RevBits Email Security enhances email security by detecting and blocking sophisticated malicious emails that get past the outer layers of an organization's email security stack. With RevBits Email Security, organizations can protect the last point of email interaction – the employee endpoint. -
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Trustwave Secure Email Gateway
Trustwave
Delivers advanced protection against today’s sophisticated email-based threats, extensive policy controls, and in-depth data security and compliance management. Protecting your email environment against spam, malware, phishing attacks, business email compromise, account takeover, ransomware and more is one of your top priorities. Trustwave Secure Email Gateway (SEG) multi-layered intelligence and detection engine performs deep analysis of your inbound email traffic, in real-time, to protect your users from cyber threats, enables you to integrate the workflow of your email content into business processes, while scrutinizing outbound email traffic to prevent the loss of your proprietary data, intellectual property, confidential documents and financial records. These security modules, used in conjunction with Secure Email Gateway, provide additional layers of protection and compliance capabilities for your business. -
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Z1 SecureMail Gateway
Zertificon
25% of the 100 German companies with the highest turnover choose Zertificon. Z1 SecureMail Gateway is our highly automated Enterprise Email Encryption solution for effortless, secure communications with anyone, anywhere. Your entire organization encrypts and decrypts, just as well manages & verifies email signatures smoothly in the background. Z1 SecureMail Gateway requires minimal maintenance. And the browser-based admin interface needs no special skills. Keys are managed automatically & central policies enforce security. Integration is fast into your Cloud or On-premises email infrastructure. Your workflows and business are uninterrupted — no employee training needed plus frictionless experience for recipients. With Z1 SecureMail Gateway, encryption is centrally configurable and proofed against human error. You easily achieve and maintain compliance and the highest security standards. You also own all encryption keys and attain German-engineered data sovereignty with no backdoors.Starting Price: from $ 1.50 per user/per month -
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ClrStream
Mithi Software Technologies
29% of businesses that face a data breach end up losing revenue. And email is the #1 target of attack. Secure your email systems with ClrStream. A security and continuity solution for MS Exchange, Office 365, MDaemon, Postfix, Postmaster, Zimbra & other mail solutions. 88% of businesses experience data loss and email is the main culprit. An email scrubbing solution with guaranteed protection from Malware, Ransomware, Virus and Spam. Low latencies for mail delivery and a low rate of false positives. A peripheral, out-of-environment solution to mitigate DDOS attacks. A solution that can provide email Continuity when the primary mail server is unavailable or down. A solution offering with built-in redundancies and scale eliminating the need for a mail parking service. A cloud-based SaaS solution that helps de-congest bandwidth and eliminates management headaches. -
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Votiro
Votiro
The only file security solution that ensures all files coming into your enterprise are completely safe. Unlike detection-based file security solutions that scan for suspicious elements and block files, Positive Selection singles out only the safe elements of each file, ensuring every file that enters your organization is 100% safe. Any file, anywhere, anytime. With a deep, expert understanding of all types of files, Votiro’s Secure File Gateway eliminates threats from the widest possible range of files, no matter how they enter your organization. -
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ePrism Email Security
EdgeWave
ePrism is a comprehensive email security gateway that provides unrivaled email defense against internal and external threats such as spam, viruses, spyware, phishing schemes, identity theft, and other dangerous or offensive content. Our services include industry leading inbound/outbound spam and antivirus filtering, category based policy and automated seamless directory integration in a hosted SaaS solution that can be provisioned immediately, without having to install any hardware or software. EdgeWave technical experts provide proactive monitoring and management designed to stop threats before they get near your internal servers. Key features include advanced threat protection, intelligent threat management, data loss prevention and compliance, disaster recovery, granular policy controls, account and domain management, complete visibility and reporting. -
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Comodo Dragon Platform
Comodo
Our completely cloud-native framework delivers you zero day protection against undetectable threats while defending your endpoints from known threat signatures. Comodo introduced a new approach to endpoint protection, engineered to solve the issue of legacy security solutions. The Dragon platform delivers the foundation principles for complete next-generation endpoint protection. Easily improve your cybersecurity and performance with the Dragon Platform's lightweight agent delivering artificial intelligence (AI) and Auto Containment to stop all threats. Comodo delivers everything cybersecurity you ever needed to activate breach protection immediate value added from day one. 100% trusted verdict within 45 seconds on 92% of signatures via analysis, and 4 hours SLA on the remaining 8% via human experts. Automatic signature updates that simplifies deployment across your entire environment to lower operational costs.
