Compare the Top On-Premises Secure Email Gateway Software as of October 2025

What is On-Premises Secure Email Gateway Software?

Secure email gateway software provides a security platform that identifies and prevents web-based threats through the use of filters and labeling. Compare and read user reviews of the best On-Premises Secure Email Gateway software currently available using the table below. This list is updated regularly.

  • 1
    Cisco Secure Email Threat Defense
    Advanced protection to safeguard your inboxes. Email is still the No. 1 threat vector. Expand the scope of your defenses to detect dangerous threats and rapidly respond to and remediate new threats in real time. Identify the malicious techniques used in attacks targeting your organization. Understand the specific business risks and categorize threats to gain insight into the parts of your organization that are most vulnerable to attack. AI-driven threat detection uses multiple detection engines to simultaneously evaluate different portions of an incoming email. These verdict details help ensure accurate threat classification, identify business risk, and promote an appropriate response action. Threats come from numerous sources: phishing, business email compromise, malware, and ransomware. Defend against all of them with industry-leading threat intelligence that empowers you to act quickly.
  • 2
    Fortinet

    Fortinet

    Fortinet

    Fortinet is a global leader in cybersecurity solutions, known for its comprehensive and integrated approach to safeguarding digital networks, devices, and applications. Founded in 2000, Fortinet provides a wide range of products and services, including firewalls, endpoint protection, intrusion prevention systems, and secure access solutions. At the core of its offerings is the Fortinet Security Fabric, a unified platform that seamlessly integrates security tools to deliver visibility, automation, and real-time threat intelligence across the entire network. Trusted by businesses, governments, and service providers worldwide, Fortinet emphasizes innovation, scalability, and performance, ensuring robust defense against evolving cyber threats while supporting digital transformation and business continuity.
  • 3
    Symantec Email Security.cloud
    Safeguard Microsoft Office 365, Google G Suite, and on-premises email with the industry’s most complete email security solution. Insulate users from spear phishing, credential theft and ransomware attacks by using Email Threat Isolation. Prevent insidious email threats such as spear phishing, ransomware, business email compromise and email spam. Stop spear phishing emails with multiple layers of protection, threat isolation, spam filtering, advanced security email analytics, built-in user awareness, education tools, and more. Block the latest ransomware with content defense, sandboxing, and link protection technologies that detect emerging, stealthy, and zero-day attacks. Defeat business email compromise with impersonation protection, sender authentication enforcement and brand protection controls. Protect your brand reputation by using automation to solve the practical issues of enforcing sender authentication (DMARC, DKIM and SPF) with Symantec Email Fraud Protection.
  • 4
    SEPPmail

    SEPPmail

    SEPPmail AG

    Sending and receiving digitally signed and encrypted emails is easier and more convenient than ever before. Thanks to the Secure E-Mail Gateway from SEPPmail with integrated and patented GINA procedure for spontaneous encryption, SMEs and large companies secure their entire e-mail communication at the highest level, with the least effort and simplest handling for sender and recipient. With its comprehensive Secure Email solution, SEPPmail is setting new standards for secure, GDPR-compliant email communication. As one of the world’s leading email encryption and signature solutions, SEPPmail includes all the features to protect the sending of confidential data via email, guarantee the authenticity of the sender and ensure the confidentiality and integrity of the message. Thanks to its modularity, the secure e-mail gateway solution can be configured according to customer-specific requirements and expanded seamlessly.
    Starting Price: 4.5 € per user per month
  • 5
    Z1 SecureMail Gateway
    25% of the 100 German companies with the highest turnover choose Zertificon. Z1 SecureMail Gateway is our highly automated Enterprise Email Encryption solution for effortless, secure communications with anyone, anywhere. Your entire organization encrypts and decrypts, just as well manages & verifies email signatures smoothly in the background. Z1 SecureMail Gateway requires minimal maintenance. And the browser-based admin interface needs no special skills. Keys are managed automatically & central policies enforce security. Integration is fast into your Cloud or On-premises email infrastructure. Your workflows and business are uninterrupted — no employee training needed plus frictionless experience for recipients. With Z1 SecureMail Gateway, encryption is centrally configurable and proofed against human error. You easily achieve and maintain compliance and the highest security standards. You also own all encryption keys and attain German-engineered data sovereignty with no backdoors.
    Starting Price: from $ 1.50 per user/per month
  • 6
    InterScan Messaging Security
    Trend Micro™ InterScan™ Messaging Security provides the most comprehensive protection against both traditional and targeted attacks. Using the correlated intelligence from Trend Micro™ Smart Protection Network™ and optional sandbox execution analysis, it blocks spam, phishing, and advanced persistent threats (APTs). The included hybrid SaaS deployment option combines a powerful gateway virtual appliance with a SaaS prefilter that stops majority of threats and spam in the cloud—closer to their source. This hybrid solution delivers the best of both worlds: the privacy and control of an on-premises appliance with an in-the-cloud pre-filter for resource efficiency and proactive protection. The Data Privacy and Encryption Module solves the toughest regulatory compliance and data protection challenges by securing outbound data. This optional module offers easy-to-use identity-based encryption and customizable data loss prevention (DLP) templates for quick deployment.
  • 7
    Trellix Email Security
    Keep your email infrastructure and users safe— whether on-premises or in the cloud. Identify and mitigate advanced email threats—including ransomware, business email compromise (BEC), and phishing—with Trellix Email Security. You’ll get leading detection and response capabilities to build a trusted, resilient email environment. Identify current threats quickly and accurately with prioritized alerts to help analysts take immediate action. Keep your email safe—whether it’s hosted on-premises or in the cloud—with leading sandbox technology, AI, and machine learning. Connect with as many as 650 Trellix solutions and third-party products to deliver insights and create a unified, living security ecosystem. Minimize the risk of breaches and identify, isolate, and protect against advanced URL and attachment-based attacks with this on-premises solution. Choose Advanced Threat mode to unearth malicious URLs with custom plug-ins, or Full Hygiene mode to reduce impersonation, BEC, and more.
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