GraphicsGale
Supports many formats, including .ico, .gif, .avi, .cur, .ani., preview your animations in real time while editing sprites - No need to stop working to watch your animation, use multiple layers to make drawing and editing your art easier, onion skinning allows you to see both previous and next frames while your draw, Output your animation frames onto a single sprite sheet, output each frame to its own image file, or export the entire animation as a single .gif file. GraphicsGale's export options are flexible enough to be compatible with any workflow, GraphicsGale also has many pixel-art specific features to help you create your work quickly and easily, including palette control, selectively erasing colors, and tools for quickly replacing and trying new colors. Free download, and get creating!
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Pro Motion NG
Pro Motion NG is a drawing software to quickly create pixel precise images, animations, sprites, tiles and level maps as used in games. It is ideal for artists working on detailed graphics as required for mobile systems like smart phones or handheld video game devices such as Nintendo DS or Sony PS Vita. It also suites well to create light weight graphics for the web or web based applications and games. Animation and image layers stack including effects, blend modes, flattening, lock.
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Pixaki
Pixaki is the best pixel art app for iPad. It packs a whole load of features into a clean, modern interface, and it works great with Apple Pencil. So now you can make game sprites on the couch, animated backgrounds on your commute, or music videos in the park. Pixaki is packed with great tools dedicated to making pixel art. Drawing on the iPad with Apple Pencil feels smooth and natural. This is the most enjoyable way you can make pixel art. Turn on pixel perfect painting mode to automatically get rid off all those nasty double pixels when doing line art. This is going to save you a ton of time. As well as round and square brushes, Pixaki comes with the matrix dither brush with 13 different dither patterns. It works with the eraser too. The line tool makes it easy to create straight lines, which can optionally be locked to angles perfect for isometric art.
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Pixen
Pixen is a professional pixel art editor designed for working with low-resolution raster art, such as those 8-bit sprites found in old-school video games. Pixen packs all the tools pixel artists need in an intuitive, native interface including support for high zoom levels, animation editing, color palettes, and a lot more.
Leverage Pixen's wide array of tools when composing pixel art: Pencil, Eraser, Brightness, Text, Eyedropper, Zoom, Rectangular Selection, Magic Wand, Lasso, Move, Fill, Line, Rectangle, and Ellipse.
Take advantage of the flexibility layers provide when working with complex pixel art. Change opacity, blending modes, and more to compose creative effects.
Use filters to adjust colors, create effects, and post-process your artwork.
With Pixen, you can add and organize commonly-used colors into palettes. Pixen can even import and export color palettes in the Adobe Color Table, Microsoft Palette, JASC Palette, and GIMP Palette formats.
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