Compare the Top Laboratory Information Systems (LIS) for Linux as of October 2025

What are Laboratory Information Systems (LIS) for Linux?

Laboratory Information Systems (LIS) are software solutions designed to manage, track, and organize data and workflows in medical and research laboratories. They streamline the handling of patient information, sample tracking, and test results, ensuring accuracy and efficiency throughout the testing process. LIS integrates with other healthcare systems, such as electronic health records (EHR), to facilitate seamless data exchange and improve clinical decision-making. The system also supports regulatory compliance by maintaining detailed records, ensuring data security, and managing quality control. Ultimately, LIS enhances lab productivity, reduces errors, and improves the overall management of laboratory operations. Compare and read user reviews of the best Laboratory Information Systems (LIS) for Linux currently available using the table below. This list is updated regularly.

  • 1
    Avalon Laboratory System

    Avalon Laboratory System

    Computer Service & Support

    Sophisticated and HIPAA-compliant, the Avalon Laboratory System is specifically designed to manage the production and billing needs of clinical, esoteric, and toxicology laboratories. Developed by Computer Service & Support(CSS), this modular laboratory information system offers an array of features for reference laboratory automation. The solution also provides a rich set of modules for microbiology, pain management and toxicology, rescheduling, remote laboratory, SQL Access, electronic medical records, pharmacogenomics, and more. In addition, there is Avalon BI (Business Intelligence) for billing. With Avalon LIS and Avalon BI running on the same platform, there is a reduction in errors and duplicate entry of data. The billing portion also offers up-front eligibility and diagnosis validity checking. In Avalon BI, there are even more robust reports for revenue cycle management.
  • 2
    Apex LIS

    Apex LIS

    Apex Healthware, LLC

    Affordable Cloud-based LIS. Perfect for startup labs! Subscriptions start at $250/month including 3 analyzer interfaces unlimited users. CLIA-compliance suite makes it easy to comply with regulatory requirements. Easy-to-use application can be installed in a day and web-training available. LIS is easily configured to meet your exact analyzer and workflow requirements. HIPAA-compliant Phone app supports patient registration, test order and results notification. We have more than 300 deployments with clients specializing in: Fertility, Genetic testing, molecular testing, Pathology, Toxicology and virtually all other specialties. We have interfaced over 250 different analyzers including interfaces to the leading analyzers in the fields of molecular biology and genetic testing.
    Starting Price: $1500 one-time payment
  • 3
    SpeedsPath AP LIS
    SpeedsPath is a cloud-native AP LIS built to streamline the entire pathology workflow—from specimen accessioning and barcode tracking to grossing, histology, reporting, and digital archiving. Unlike outdated LIS systems that require heavy IT infrastructure, SpeedsPath is hosted in the cloud, making it accessible, scalable, and cost-efficient. Our platform provides pathology labs with a centralized, secure, and user-friendly system that automates routine processes, reduces manual errors, and ensures compliance with regulatory requirements like HIPAA, CLIA, and CAP.
    Starting Price: $0
  • 4
    SurroundLab

    SurroundLab

    Seacoast Laboratory Data Systems

    SurroundLab™ Plus is a fully customizable, feature-rich laboratory information system designed for the commercial marketplace. Now you can offer your clients the personal attention they require. The ability to completely customize reports to client specifications and deliver them where and when they want them is just the beginning of how SurroundLab Plus can empower your laboratory and your client. The Seacoast philosophy has always been that each client represents a unique business challenge. SurroundLab Plus was built to let you run your business the way you see fit. Master Patient ID. Rules based automated duplicate. Order processing logic. ABN checking and print. Patient ‘balance due’ alerts and Easy Pay for upfront collection of Patient CC Payments. Rapid receipt for HL7 inbound orders. 2-D bar code scan for Lab Connect Orders. Bar-coded specimen labels. Custom algorithms for complex result interpretations.
    Starting Price: $60000.00/month
  • 5
    Labgen LIS

    Labgen LIS

    Comtron

    Comtron Inc. has been a provider of quality software products since 1987. Our experience in the medical field allows us to use the latest in technology to solve many of today's challenges facing the medical professionals. Ideal for any size practice and laboratories, from the multi-provider enterprise to a solo practitioner, small lab to regional reference laboratory Comtron's proven suite of applications streamline front and back office administration and manage all clinical data
  • 6
    Clinisys Laboratory Platform
    HORIZON is now Clinisys, the number one provider of laboratory information systems across the globe. Clinisys brings together laboratory information system expertize across the globe to offer flexible laboratory solutions across healthcare, environment, toxicology and public health, pharma and biotech. The full capabilities of HORIZON LIMS now form the basis of the Clinisys Laboratory Platform a robust, affordable, data-centric software platform built to configure and integrate with every kind of lab. HORIZON LIMS is now known as Clinisys Laboratory Platform and meets the needs of a wide variety of lab challenges. From the samples you test to the way you operate, each lab has unique features that make them great at what they do. Clinisys Laboratory Platform configures to suit and integrate specifically with your lab. HORIZON LIMS is now known as Clinisys Laboratory Platform and meets the needs of a wide variety of lab challenges.
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