Best IoT Security Software for Microsoft 365
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Compare the Top IoT Security Software that integrates with Microsoft 365 as of October 2025
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This a list of IoT Security software that integrates with Microsoft 365. Use the filters on the left to add additional filters for products that have integrations with Microsoft 365. View the products that work with Microsoft 365 in the table below.
What is IoT Security Software for Microsoft 365?
IoT (Internet of Things) security software is designed to protect connected devices and networks from cyber threats, ensuring the confidentiality, integrity, and availability of data transmitted between IoT devices. These tools monitor and secure devices, applications, and networks that are part of the IoT ecosystem, which includes sensors, actuators, smart appliances, wearables, and industrial equipment. IoT security software includes features such as threat detection, data encryption, access control, device authentication, and vulnerability management to mitigate risks from cyberattacks, unauthorized access, and data breaches. It is essential for industries like healthcare, manufacturing, transportation, and smart cities, where the IoT devices are widely used and often contain sensitive or critical data. Compare and read user reviews of the best IoT Security software for Microsoft 365 currently available using the table below. This list is updated regularly.
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1
Microsoft Defender for IoT
Microsoft
Accelerate digital transformation with comprehensive security across your IoT/OT infrastructure. Microsoft Defender for IoT offers agentless network detection and response (NDR) that is rapidly deployed, works with diverse IoT, OT, and industrial control system (ICS) devices, and interoperates with Microsoft 365 Defender, Microsoft Sentinel, and external security operations center (SOC) tools. Deploy on-premises or via cloud. For IoT device builders, Defender for IoT offers lightweight agents for stronger device-layer security. Use passive, agentless network monitoring to safely gain a complete inventory of all your IoT/OT assets, with zero impact on IoT/OT performance. Analyze diverse and proprietary industrial protocols to visualize your IoT/OT network topology and see communication paths, and then use that information to accelerate network segmentation and zero trust initiatives.Starting Price: $0.001 per device per month -
2
Armis
Armis Security
Armis, the leading asset visibility and security company, provides the industry’s first unified asset intelligence platform designed to address the new extended attack surface that connected assets create. Fortune 100 companies trust our real-time and continuous protection to see with full context all managed, unmanaged assets across IT, cloud, IoT devices, medical devices (IoMT), operational technology (OT), industrial control systems (ICS), and 5G. Armis provides passive cyber asset management, risk management, and automated enforcement. Armis is a privately held company and headquartered in California. -
3
Darktrace
Darktrace
Darktrace is a cybersecurity platform powered by AI, providing a proactive approach to cyber resilience. Its ActiveAI Security Platform delivers real-time threat detection, autonomous responses to both known and novel threats, and comprehensive visibility into an organization’s security posture. By ingesting enterprise data from native and third-party sources, Darktrace correlates security incidents across business operations and detects previously unseen threats. This complete visibility and automation reduce containment time, eliminate alert fatigue, and significantly enhance the efficiency of security operations. -
4
Tenable One
Tenable
Tenable One radically unifies security visibility, insight and action across the attack surface, equipping modern organizations to isolate and eradicate priority cyber exposures from IT infrastructure to cloud environments to critical infrastructure and everywhere in between. The world’s only AI-powered exposure management platform. See every asset across your entire attack surface—from cloud environments to operational technologies, infrastructure to containers, and remote workers to modern web-apps with Tenable's market-leading vulnerability management sensors. With more than 20 trillion aspects of threat, vulnerability, misconfiguration and asset information, Tenable’s machine-learning powered predictions reduce remediation efforts by enabling you to focus first on the risks that matter most. Drive improvements required to reduce the probability of a business-impacting cyber event from occurring by communicating objective measures of risk. -
5
Medigate
Medigate
Healthcare’s Security and Clinical Analytics Company. #1 IoT device security solution designed for Healthcare. Medigate has invested in building out the largest medical device and protocol database so you can have the most detailed device inventories and accurate threat detection available. Medigate offers the industry’s only truly dedicated medical device security platform that identifies and protects all Internet of Medical Things (IoMT) devices connected to a healthcare provider’s network. Unlike general IoT solutions, we’ve built our cyber security platform specifically and only for the unique needs of medical devices and clinical networks. Our solution safeguards clinical networks from all angles by providing complete visibility into all connected medical devices to identify risk based on clinical context, detect anomalies according to manufacturers’ protocols and actively block malicious activities by integrating into your existing firewalls or NAC. -
6
SASE is a vision of converged technologies to improve network performance and security for users who can be anywhere, use any device, and need access to content and applications from corporate data centers and cloud platforms. Symantec can help you achieve all of the benefits of digital transformation and SASE through low-latency cloud and internet access, as well as a complete range of integrated best-in-class network security capabilities. Get advanced, cloud-delivered network security service to enforce consistent web and cloud application security and compliance policies for all users, regardless of location and device. Prevent loss of sensitive data and exfiltration of intellectual property at the service edge. Protect your applications and resources from unauthorized access, network-based attacks, and lateral movement with Zero Trust Network Access (ZTNA) technology.
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