Best HPC Software for AWS Deep Learning AMIs

Compare the Top HPC Software that integrates with AWS Deep Learning AMIs as of October 2025

This a list of HPC software that integrates with AWS Deep Learning AMIs. Use the filters on the left to add additional filters for products that have integrations with AWS Deep Learning AMIs. View the products that work with AWS Deep Learning AMIs in the table below.

What is HPC Software for AWS Deep Learning AMIs?

High-Performance Computing (HPC) software are applications designed to maximize computational power, enabling complex and resource-intensive tasks to be executed efficiently. These programs optimize parallel processing, often leveraging supercomputers or distributed computing clusters to solve problems in fields like scientific research, engineering, and data analytics. HPC software includes components for workload management, data communication, and performance tuning, ensuring scalability and efficient resource utilization. Examples include simulation software, machine learning frameworks, and tools for weather modeling or molecular dynamics. By harnessing advanced algorithms and hardware, HPC software accelerates computation, reducing the time required for tasks that would otherwise take weeks or months on conventional systems. Compare and read user reviews of the best HPC software for AWS Deep Learning AMIs currently available using the table below. This list is updated regularly.

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    Amazon EC2 P4 Instances
    Amazon EC2 P4d instances deliver high performance for machine learning training and high-performance computing applications in the cloud. Powered by NVIDIA A100 Tensor Core GPUs, they offer industry-leading throughput and low-latency networking, supporting 400 Gbps instance networking. P4d instances provide up to 60% lower cost to train ML models, with an average of 2.5x better performance for deep learning models compared to previous-generation P3 and P3dn instances. Deployed in hyperscale clusters called Amazon EC2 UltraClusters, P4d instances combine high-performance computing, networking, and storage, enabling users to scale from a few to thousands of NVIDIA A100 GPUs based on project needs. Researchers, data scientists, and developers can utilize P4d instances to train ML models for use cases such as natural language processing, object detection and classification, and recommendation engines, as well as to run HPC applications like pharmaceutical discovery and more.
    Starting Price: $11.57 per hour
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