Best HPC Software for Amazon

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Compare the Top HPC Software that integrates with Amazon as of October 2025

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This a list of HPC software that integrates with Amazon. Use the filters on the left to add additional filters for products that have integrations with Amazon. View the products that work with Amazon in the table below.

What is HPC Software for Amazon?

High-Performance Computing (HPC) software are applications designed to maximize computational power, enabling complex and resource-intensive tasks to be executed efficiently. These programs optimize parallel processing, often leveraging supercomputers or distributed computing clusters to solve problems in fields like scientific research, engineering, and data analytics. HPC software includes components for workload management, data communication, and performance tuning, ensuring scalability and efficient resource utilization. Examples include simulation software, machine learning frameworks, and tools for weather modeling or molecular dynamics. By harnessing advanced algorithms and hardware, HPC software accelerates computation, reducing the time required for tasks that would otherwise take weeks or months on conventional systems. Compare and read user reviews of the best HPC software for Amazon currently available using the table below. This list is updated regularly.

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    AWS Elastic Fabric Adapter (EFA)
    Elastic Fabric Adapter (EFA) is a network interface for Amazon EC2 instances that enables customers to run applications requiring high levels of inter-node communications at scale on AWS. Its custom-built operating system (OS) bypass hardware interface enhances the performance of inter-instance communications, which is critical to scaling these applications. With EFA, High-Performance Computing (HPC) applications using the Message Passing Interface (MPI) and Machine Learning (ML) applications using NVIDIA Collective Communications Library (NCCL) can scale to thousands of CPUs or GPUs. As a result, you get the application performance of on-premises HPC clusters with the on-demand elasticity and flexibility of the AWS cloud. EFA is available as an optional EC2 networking feature that you can enable on any supported EC2 instance at no additional cost. Plus, it works with the most commonly used interfaces, APIs, and libraries for inter-node communications.
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