PyBullet is a Python module for physics simulation, robotics, and deep reinforcement learning, built on the Bullet Physics SDK. It supports loading articulated bodies from URDF, SDF, and other formats, providing forward dynamics simulation, inverse dynamics computation, kinematics, collision detection, and ray intersection queries. PyBullet offers rendering capabilities, including a CPU renderer and OpenGL visualization, with support for virtual reality headsets. It is utilized in various research projects, such as Assistive Gym, which leverages PyBullet for physical human-robot interaction and assistive robotics, supporting collaborative robots and physically assistive tasks. Another project, Kubric, is an open source Python framework interfacing with PyBullet and Blender to generate photo-realistic scenes with rich annotations, scaling to large jobs distributed over thousands of machines.