Best Encryption Software for Microsoft 365

Compare the Top Encryption Software that integrates with Microsoft 365 as of October 2025

This a list of Encryption software that integrates with Microsoft 365. Use the filters on the left to add additional filters for products that have integrations with Microsoft 365. View the products that work with Microsoft 365 in the table below.

What is Encryption Software for Microsoft 365?

Encryption software allows companies to protect and secure data using cryptography to protect valuable files and sensitive data and enhance security. Compare and read user reviews of the best Encryption software for Microsoft 365 currently available using the table below. This list is updated regularly.

  • 1
    Files.com

    Files.com

    Files.com

    6,000+ companies trust Files.com to automate and secure business critical transfers. We obsess about security, compliance, reliability, and performance so your critical business processes just work every time. Easily manage any transfer flow without writing scripts or code, and onboard workloads and partners effortlessly. We support standard file transfer protocols (FTP, SFTP, AS2) for working with external partners and also provide native apps for high performance internal transfers. As a fully Cloud-Native SaaS, there are no servers for you to buy or maintain, there is no installation required, and high availability and redundancy are built in and free. Out-of-the-box integrations include Microsoft (Azure, SharePoint, OneDrive, Active Directory & Office), AWS (S3 & SNS), Google (Cloud & Drive), Box, Dropbox, Zapier, and dozens of others. Developers can leverage our SDKs, API, and CLI to build custom integrations too.
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  • 2
    SharePass

    SharePass

    SharePass

    SharePass is a SaaS Secret Management platform that allows sharing and managing secrets and confidential information using a web application, extension, or mobile app. SharePass works with encrypted links transmitted from the sender to the receiver with various settings and flags. The settings include expiry restriction, availability, IP restrictions and an entire filtering funnel (patent pending). SharePass is platform-independent that can be used with your existing communication tools. When it comes to your privacy, SharePass or any of its employees cannot see the content of your secrets; the secrets can be seen only by the exchanging parties. SharePass meets the latest cybersecurity compliance and regulations. In the era of identity theft, SharePass will protect you and prevent your data from leaking to the dark web by eliminating your digital footprint. SharePass supports SSO with Office365, Google Workspace, MFA, and integration with Yubikeys for maximum security.
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    Starting Price: Free
  • 3
    N-able Mail Assure
    N-able Mail Assure cloud-based email security solution provides advanced threat protection for inbound and outbound email using collective threat intelligence, 24/7 email continuity, and long-term email archiving. The service includes a multitenant web-interface with predefined settings, reporting, and views designed to ensure control and visibility over email flows. N-able Mail Assure’s proprietary technology incorporates input from processing large volumes of email data that feeds the Intelligent Protection and Filtering Engine. This combined with real-time pattern threat recognition leveraging a variety of filtering technologies help protect against spam, viruses, phishing attacks, impersonation, spoofing, malware, and other email-borne threats.
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    BitLocker

    BitLocker

    Microsoft

    BitLocker Drive Encryption is a data protection feature that integrates with the operating system and addresses the threats of data theft or exposure from lost, stolen, or inappropriately decommissioned computers. BitLocker provides the most protection when used with a Trusted Platform Module (TPM) version 1.2 or later. The TPM is a hardware component installed in many newer computers by the computer manufacturers. It works with BitLocker to help protect user data and to ensure that a computer has not been tampered with while the system was offline. On computers that do not have a TPM version 1.2 or later, you can still use BitLocker to encrypt the Windows operating system drive. However, this implementation will require the user to insert a USB startup key to start the computer or resume from hibernation. Starting with Windows 8, you can use an operating system volume password to protect the operating system volume on a computer without TPM.
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    WinZip SafeShare
    A modernized sharing experience. Share your files with confidence and security in an intuitive environment built with simplicity in mind. This powerful sharing tool allows you to share, compress, and encrypt, all within a simple interface. Easily share files to one or many locations, surrounded by extra layers of security, including military-grade encryption and time bomb capabilities. Enjoy expanded cloud services, including OpenStack and SwiftStack regions and credential files, Alibaba, Wasabi, HP, Oracle, Azure, WebDAV, CenturyLink, IONOS and OVH cloud providers. Combine multiple PDF files into a single PDF file to save, zip, or share. Streamline workflow when sharing via Slack IM. Manage files shared by WinZip or ZipShare. Open and view, share again or remove shared files. Keep track of which Zip files you have shared via WinZip or ZipShare. Email anyone directly from WinZip by adding contacts from all your supported sources into one combined address book.
    Starting Price: $34.95 one-time payment
  • 6
    ESET PROTECT Elite
    ESET PROTECT Elite is an enterprise-grade cybersecurity solution that integrates extended detection and response with comprehensive multilayered protection. It offers advanced threat defense using adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis to prevent zero-day threats and ransomware. The platform includes modern endpoint protection for computers and smartphones, server security for real-time data protection, and mobile threat defense. It also features full disk encryption, helping organizations comply with data protection regulations. ESET PROTECT Elite provides robust email security, including anti-phishing, anti-malware, and anti-spam technologies, along with cloud app protection for Microsoft 365 and Google Workspace. Vulnerability and patch management capabilities allow for automatic tracking and patching of vulnerabilities across all endpoints.
    Starting Price: $275 one-time payment
  • 7
    IBM Guardium Data Encryption
    Protect your file and database data from misuse and help comply with industry and government regulations with this suite of integrated encryption products. IBM Guardium Data Encryption consists of an integrated suite of products built on a common infrastructure. These highly-scalable solutions provide encryption, tokenization, data masking and key management capabilities to help protect and control access to databases, files and containers across the hybrid multicloud—securing assets residing in cloud, virtual, big data and on-premise environments. Securely encrypting file and database data with such functionalities as tokenization, data masking and key rotation can help organizations address compliance with government and industry regulations, including GDPR, CCPA, PCI DSS and HIPAA. Guardium Data Encryption's capabilities—such as data access audit logging, tokenization, data masking and key management—help meet regulations such as HIPAA, CCPA or GDPR.
  • 8
    WinZip SafeMedia
    Employees need the flexibility to take digital data with them wherever they go. Businesses must ensure this data is always secured. WinZip SafeMedia enables users to quickly and safely store, manage, and transport files on removable media (e.g., removable storage devices such as CDs, DVDs, and USB drives and sticks), empowering IT admins to uphold protocols and standards that defend your business against online and offline threats. Tailor security policies to your organization’s needs. Customize settings for individuals or groups, and monitor activity as needed. Use drag and drop plus automatic security features to provide end users with a simple, easy solution that doesn’t hinder productivity. Leverage FIPS 140-2 compliant and FIPS 197 certified encryption and compression to protect data on removable media. Best-in-class encryption methodologies protect classified information while enabling storage flexibility and centralized control.
  • 9
    OpenText ZENworks Full Disk Encryption
    OpenText ZENworks Full Disk Encryption enables you to centrally enforce policies for encrypting entire hard disks on Windows 7, Windows 8, and Windows 10 machines in your organization. You manage them using the same web-based console and adaptive agent that you use for other ZENworks products. Protect your company data with the proven reliability of encrypting the entire hard disk drive. Ensure that encrypted devices remain easy to manage across the enterprise. You can remotely unlock devices that are protected by full disk encryption and keep users productive while they work remotely. Ensure that you meet critical industry guidelines and government regulations for protecting customer and patient data. Leverage your experience with ZENworks to reduce the cost of implementing Full Disk Encryption.
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