Best Encryption Key Management Software for Microsoft 365

Compare the Top Encryption Key Management Software that integrates with Microsoft 365 as of October 2025

This a list of Encryption Key Management software that integrates with Microsoft 365. Use the filters on the left to add additional filters for products that have integrations with Microsoft 365. View the products that work with Microsoft 365 in the table below.

What is Encryption Key Management Software for Microsoft 365?

Encryption key management software securely handles the creation, storage, distribution, and lifecycle management of encryption keys used to protect sensitive data. It provides a centralized system that ensures only authorized users and applications can access or decrypt encrypted information, reducing the risk of data breaches. By automating key processes such as generation, rotation, expiration, and backup, this software helps maintain security standards and compliance with regulatory requirements. With features like role-based access, logging, and auditing, it offers transparency and control over key usage. Encryption key management is essential for organizations aiming to secure data across databases, applications, and cloud environments. Compare and read user reviews of the best Encryption Key Management software for Microsoft 365 currently available using the table below. This list is updated regularly.

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    Keeper Security

    Keeper Security

    Keeper Security

    Keeper Security is transforming the way people and organizations around the world secure their passwords and passkeys, secrets and confidential information. Keeper’s easy-to-use cybersecurity platform is built on a foundation of zero-trust and zero-knowledge security to protect every user on every device. Keeper’s solution deploys in minutes and seamlessly integrates with any tech stack to prevent breaches, reduce help desk costs and ensure compliance. Trusted by millions of individuals and thousands of organizations globally, Keeper is the leader for best-in-class password and passkey management, secrets management, privileged access, secure remote access and encrypted messaging. Protect what matters at KeeperSecurity.com.
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    Starting Price: $2.00 per user, per month
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  • 2
    Egnyte

    Egnyte

    Egnyte

    Egnyte provides a unified content security and governance solution for collaboration, data security, compliance, and threat detection for multicloud businesses. More than 16,000 organizations trust Egnyte to reduce risks and IT complexity, prevent ransomware and IP theft, and boost employee productivity on any app, any cloud, anywhere.
    Starting Price: $10 per user per month
  • 3
    Zoho Vault
    Say goodbye to memorizing passwords. Let us do it for you. Zoho Vault is a secure password manager that safely manages your passwords and autofills them across websites and applications. Unlimited password storage, seamless autofill, fine-grained admin controls–Vault has it all. Get clear security insights into both your personal and business passwords. Identify any weak passwords and change them in just a few clicks. Securely store, share, and manage passwords with different levels of access privileges. You can also add notes, documents, credit cards, software licenses, SSH keys, and more to your password vault. Organize passwords and other confidential data into groups as folders and sub-folders for easy password management and bulk-sharing. Allow users to log in to their everyday apps without passwords. Our catalog readily supports hundreds of popular cloud apps, as well as options for custom integration.
    Starting Price: $1 per month
  • 4
    IBM Guardium Data Encryption
    Protect your file and database data from misuse and help comply with industry and government regulations with this suite of integrated encryption products. IBM Guardium Data Encryption consists of an integrated suite of products built on a common infrastructure. These highly-scalable solutions provide encryption, tokenization, data masking and key management capabilities to help protect and control access to databases, files and containers across the hybrid multicloud—securing assets residing in cloud, virtual, big data and on-premise environments. Securely encrypting file and database data with such functionalities as tokenization, data masking and key rotation can help organizations address compliance with government and industry regulations, including GDPR, CCPA, PCI DSS and HIPAA. Guardium Data Encryption's capabilities—such as data access audit logging, tokenization, data masking and key management—help meet regulations such as HIPAA, CCPA or GDPR.
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    Alliance Key Manager

    Alliance Key Manager

    Townsend Security

    Once data is encrypted, your private information depends on enterprise-level key management to keep that data safe. The solution provides high availability, standards-based enterprise encryption key management to a wide range of applications and databases. Alliance Key Manager is a FIPS 140-2 compliant enterprise key manager that helps organizations meet compliance requirements and protect private information. The symmetric encryption key management solution creates, manages, and distributes 128-bit, 192-bit, and 256-bit AES keys for any application or database running on any Enterprise operating system. Encryption keys can be restricted based on several criteria. The most permissive level requires a secure and authenticated TLS session to the key server. Individual encryption keys can be restricted to users, groups, or specific users in groups. Enterprise-wide groups can be defined and keys can be restricted to Enterprise users, groups, or specific users in groups.
    Starting Price: $4,800 one-time payment
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