Best Email Security Software for Microsoft OneDrive

Compare the Top Email Security Software that integrates with Microsoft OneDrive as of October 2025

This a list of Email Security software that integrates with Microsoft OneDrive. Use the filters on the left to add additional filters for products that have integrations with Microsoft OneDrive. View the products that work with Microsoft OneDrive in the table below.

What is Email Security Software for Microsoft OneDrive?

Email security software protects organizations from cyber threats such as phishing, malware, and spam by filtering incoming and outgoing email traffic. It uses advanced threat detection, encryption, and data loss prevention (DLP) to safeguard sensitive information. These tools also offer features like email authentication (DMARC, SPF, DKIM) and real-time threat intelligence to block emerging attacks. By securing email communications, businesses can prevent data breaches, ensure regulatory compliance, and maintain user trust. Email security software is essential for mitigating human error, which is one of the leading causes of data breaches. Compare and read user reviews of the best Email Security software for Microsoft OneDrive currently available using the table below. This list is updated regularly.

  • 1
    Checkpoint Anti-Spam and Email Security

    Checkpoint Anti-Spam and Email Security

    Check Point Software Technologies

    Check Point Anti-Spam & Email Security provides comprehensive protection for messaging infrastructure. A multidimensional approach protects email infrastructure, provides highly accurate anti-spam coverage and defends organizations from a wide variety of virus and malware threats delivered within email. Comprehensive email security with 97% spam detection. Advanced anti-spam protection, including content-based and via IP reputation. Offers antivirus protection with both zero-hour and signature-based detection. Email IPS protection against Denial of Service (DoS), buffer over-flow attacks. Simplified configuration and management of mail security. Simple configuration with low management-overhead. Full user control with no user installation required. Real-time detection and updates provide immediate protection from outbreaks. Integrated into the Check Point Infinity Architecture. Activate Anti-spam and email security on any check point security gateway.
  • 2
    ESET Cloud Office Security
    Preventive protection for cloud-based applications such as email, collaboration, and storage. A powerful combination of spam filtering, anti‑malware scanning, anti‑phishing, and advanced threat defense capabilities. Equip your Microsoft 365 Exchange Online, OneDrive, Teams, and SharePoint Online with an extra layer of advanced protection. Helps eliminate unsolicited emails, targeted attacks, and ransomware, allowing employees to focus on their jobs and ensure business continuity. Get immediate notifications direct to your dedicated console, or via alerts. New users are protected automatically. Provides advanced protection for Microsoft 365 applications against malware, spam, or phishing attacks with ultimate zero-day threat defense and an easy-to-use cloud management console. Now using an enhanced, award-winning engine with improved performance, this essential component filters all spam emails and keeps user mailboxes free of unsolicited or undesired messages.
    Starting Price: $119.50 per year
  • 3
    Avanan

    Avanan

    Check Point

    Enterprise AI cloud security: prevent phishing, malware, data leakage, account takeover, & shadow IT for full-suite cloud applications like Office 365™. Default security misses far too many malicious emails, necessitating advanced email security to protect the enterprise. Avanan reinvented email security in 2015 because traditional gateways couldn’t, and haven’t, adjusted to the cloud. Avanan’s patented security. Security for all your collaboration apps. Ransomware, account takeover, BEC, supply chain attacks. 99.2% reduction in phishing attacks reaching the inbox. Avanan is powered by True AI, trained on comprehensive data sets to stop the most sophisticated phishing attacks before they reach the inbox. To implement API, machine learning and AI for cloud email security. 5,000+ customers, 60% coming from large enterprise. Ranked Email Security solution in Gartner Peer Insights and G2.
  • 4
    ManageEngine M365 Manager Plus
    M365 Manager Plus is an extensive Microsoft 365 tool used for reporting, managing, monitoring, auditing, and creating alerts for critical activities. With its user-friendly interface, you can easily manage Exchange Online, Azure Active Directory, Skype for Business, OneDrive for Business, Microsoft Teams, and other Microsoft 365 services all from one place. M365 Manager Plus provides exhaustive preconfigured reports on Microsoft 365 and helps you perform complex tasks including bulk user management, bulk mailbox management, secure delegation, and more. Monitor Microsoft 365 services around the clock, and receive instant email notifications about service outages. M365 Manager Plus eases compliance management with built-in compliance reports and offers advanced auditing and alerting features to keep your Microsoft 365 setup secure.
    Starting Price: $345 per year
  • 5
    BooleBox

    BooleBox

    Boole Server

    BooleBox is a content security platform that maintains clients data integrity and confidentiality from unauthorized access while ensuring the highest level of encryption to protect sensitive data from attacks. Thanks to an advanced encryption system and various security settings, users can finally create, edit, share and classify files and folders, without compromising the usability. With boolebox solutions, we protect your data wherever it is, at work, in the cloud, in transit via e-mail, in shared projects, and in the most commonly used platforms, such as Windows, Outlook, Gmail, OneDrive, and SharePoint. We understand your potential digital vulnerabilities, and we protect them like no one else can because our protection is the bodyguard of your data. It never abandons it and follows it everywhere! We protect large amounts of data in different types of business sectors. We have been doing this every day since 2011.
  • 6
    mxHERO

    mxHERO

    mxHERO

    The leading enterprise technology for email attachment security integrating your email and cloud storage services. mxHERO replaces email attachments with secure cloud storage links so that sensitive files are no longer sent and stored unprotected outside the organization - as they are in standard email. Email can expose sensitive content inside & outside the organization. mxHERO ensures that all email content is managed via client preferred content platforms. mxHERO automatically moves file attachments to cloud storage – keeping valuable digital files out of email – solving for content sprawl, version control, and file size issues. Reduces breach risks with in-flight or at-rest email assets. mxHERO's customers include major global brands and industry leading enterprises. Email is a major security problem but core to how business gets done. mxHERO's clients need to make their existing email more secure without introducing disruptive changes to their employees or customers.
    Starting Price: $5 month/user
  • 7
    Darktrace

    Darktrace

    Darktrace

    Darktrace is a cybersecurity platform powered by AI, providing a proactive approach to cyber resilience. Its ActiveAI Security Platform delivers real-time threat detection, autonomous responses to both known and novel threats, and comprehensive visibility into an organization’s security posture. By ingesting enterprise data from native and third-party sources, Darktrace correlates security incidents across business operations and detects previously unseen threats. This complete visibility and automation reduce containment time, eliminate alert fatigue, and significantly enhance the efficiency of security operations.
  • 8
    Armorblox

    Armorblox

    Armorblox

    Armorblox uses natural language understanding, deep learning, and statistical techniques to protect all enterprise communications from inbound threats and outbound data loss. The Armorblox platform leverages a broad spectrum of data sources, signals, and detection techniques. Stop business email compromise, account takeover, executive impersonation, and other targeted threats. Study detailed attack analysis that’s built for human eyes. Automatically delete, quarantine, or label emails based on preconfigured policies. Detect PII/PCI violations and passwords disclosed through emails. Block outbound emails containing confidential information. Prevent lateral data leaks across email, messaging, and file-sharing solutions. Auto-remediate all reported false positives. Remove similar suspicious emails across user mailboxes with one click. Leverage dynamic policies to stop similar attacks in the future.
  • 9
    Datto SaaS Protection

    Datto SaaS Protection

    Datto, a Kaseya company

    Reliably and securely backup Microsoft 365 and Google Workspace (formerly G Suite) to ensure critical programs used for business, email and docs are protected from every day downtime events and cyber threats. Datto SaaS Protection is a cloud-to-cloud backup solution built exclusively for MSPs, protecting thousands of businesses today. Datto SaaS Protection offers comprehensive backup, recovery and overall cyber resiliency for critical cloud data that lives in Microsoft 365 and Google Workspace applications. Protect against permanent data loss and recover from ransomware or user-error quickly with one-click restore. Get new clients up and running fast with streamlined onboarding and manage client backups from a single pane of glass. Discounts are applied to the total licenses sold across all of your clients, meaning that, the more you sell, the more you’ll make. Meet business continuity, compliance, and security requirements beyond Microsoft 365 and Google Workspace.
  • 10
    GBS iQ.Suite
    The use of collaboration tools and meeting platforms from vendors such as Microsoft and CISCO is constantly increasing, and with it the security measures that need to be taken. As more and more channels, more complex IT infrastructures and a large part of the platforms run entirely in the cloud, new gateways and attack vectors are emerging. While most organizations are constantly increasing their email security measurements, they often tend to overlook protection against malicious files, that enter the company via SharePoint or messenger, for example. The security capabilities currently available are often limited and ineffective. The platforms helps companies respond promptly to the dynamic and ever-changing threat landscape with a centralized cloud solution that fits both enterprises and small companies.
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