Best Email Encryption Software for Microsoft Exchange

Compare the Top Email Encryption Software that integrates with Microsoft Exchange as of October 2025

This a list of Email Encryption software that integrates with Microsoft Exchange. Use the filters on the left to add additional filters for products that have integrations with Microsoft Exchange. View the products that work with Microsoft Exchange in the table below.

What is Email Encryption Software for Microsoft Exchange?

Email encryption software ensures the confidentiality and integrity of email communications by converting messages into unreadable formats that can only be decrypted by authorized recipients. It uses encryption protocols such as S/MIME and PGP to protect sensitive information from interception, eavesdropping, and unauthorized access. The software helps organizations comply with data privacy regulations like GDPR, HIPAA, and CCPA by securing emails containing personal or financial information. Email encryption can be applied at the message level, attachment level, or entire inbox, providing versatile protection for both internal and external communications. By safeguarding email content, businesses can reduce the risk of data breaches, maintain customer trust, and avoid costly compliance fines. Compare and read user reviews of the best Email Encryption software for Microsoft Exchange currently available using the table below. This list is updated regularly.

  • 1
    Mimecast Advanced Email Security
    Mimecast Advanced Email Security is a robust solution designed to protect organizations from a wide range of email-based threats, including phishing, malware, impersonation attacks, and spam. Leveraging cutting-edge AI and machine learning, Mimecast provides real-time threat detection and prevention to safeguard sensitive information and ensure business continuity. It offers advanced filtering and scanning of incoming and outgoing emails, reducing the risk of data breaches, and helps organizations comply with regulatory requirements. With comprehensive reporting and management tools, Mimecast enables IT teams to efficiently monitor and respond to potential threats, making it a trusted choice for businesses seeking enhanced email security.
  • 2
    Proofpoint Email Protection
    Proofpoint Email Protection solutions—deployed as a cloud service or on-premises—protect against malware and threats that don't involve malware, including impostor email, or business email compromise (BEC). Granular email filtering controls spam, bulk "graymail" and another unwanted email. And continuity capabilities keep email communications flowing when your email server fails. Proofpoint Email Protection is the industry-leading email gateway, which can be deployed as a cloud service or on premises. It catches both known and unknown threats that others miss. Powered by NexusAI, our advanced machine learning technology, Email Protection accurately classifies various types of email. And it detects and blocks threats that don’t involve malicious payload, such as impostor email—also known as business email compromise (BEC)—using our Advanced BEC Defense. You can also automatically tag suspicious email to help raise user awareness. And you can track down any email in seconds.
  • 3
    SecurityGateway™ for Email Servers
    Developed by MDaemon Technologies, an email industry pioneer, Security Gateway's email threat detection technology has been protecting email servers from viruses, spam, phishing, data loss and other threats for over 20 years. Simply put, companies trust our expertise to help keep email communications safe. We protect all email platforms including Microsoft Exchange, Office 365 and others. Let our team of email security experts take the headache out of managing your company's email security needs. Security Gateway uses the latest email threat detection technology and policy enforcement tools to keep good emails flowing to and from your users. The Security Gateway cloud service can be deployed quickly and easily, allowing you to focus on other important tasks. Watch a short video to learn about some of the Security Gateway features.
    Starting Price: $1 per user per month
  • 4
    Spambrella

    Spambrella

    Spambrella

    Dynamically classify imposter email. Preemptively identify and sandbox suspicious URLs. Leverage big-data analysis to accurately classify bulk mail. All within a single service that connects with Microsoft 365 and Google Workspace. Spambrella’s Email Security and User Awareness Training technology is used by some of the World’s largest and most successful security-conscious companies in a multitude of continents and environments. Delivered on a global scale, Spambrella is ready to unify your email security and user awareness training requirements. Think of us as your outsourced email security team! We have deep technical expertise of all other service providers such as MxLogic, Mimecast, Symantec.cloud and know how to migrate you effortlessly. Schedule a demo today with our cybersecurity experts to uncover email threats targeting your email users.
    Starting Price: $1.00
  • 5
    EncryptTitan
    EncryptTitan is a 100% cloud based encryption system for MSPs & Enterprises that allows users to exchange information securely via email.  EncryptTitan provides organizations with the tools needed to adhere to state and federal privacy regulations while protecting their organization. EncryptTitan has pre-built DLP policies and settings that will look for regular content in the message body or attachment to automatically encrypt messages. Meet compliance requirements for protecting sensitive, private information. Providing data breach protection and avoiding costly fines and penalties. The outlook plug in can be used with our keyword encryption deployment, where the user can select which emails to be encrypted for the add in. EncryptTitan helps the safeguarding of private information & avoidance of litigation & bad press which can impact customer trust. Book your demo today and learn more about EncryptTitan.
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