Best Email Encryption Software for Microsoft 365
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Compare the Top Email Encryption Software that integrates with Microsoft 365 as of October 2025
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This a list of Email Encryption software that integrates with Microsoft 365. Use the filters on the left to add additional filters for products that have integrations with Microsoft 365. View the products that work with Microsoft 365 in the table below.
What is Email Encryption Software for Microsoft 365?
Email encryption software ensures the confidentiality and integrity of email communications by converting messages into unreadable formats that can only be decrypted by authorized recipients. It uses encryption protocols such as S/MIME and PGP to protect sensitive information from interception, eavesdropping, and unauthorized access. The software helps organizations comply with data privacy regulations like GDPR, HIPAA, and CCPA by securing emails containing personal or financial information. Email encryption can be applied at the message level, attachment level, or entire inbox, providing versatile protection for both internal and external communications. By safeguarding email content, businesses can reduce the risk of data breaches, maintain customer trust, and avoid costly compliance fines. Compare and read user reviews of the best Email Encryption software for Microsoft 365 currently available using the table below. This list is updated regularly.
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1
NeoCertified Secure Email
NeoCertified
NeoCertified protects sensitive information through our secure email application across our versatile Cloud-based platform on any web browser, through Microsoft Office 365/Outlook plug-ins, and Gmail integration. iPhone + Android mobile apps are also available directly on your mobile devices. We have provided federally compliant, secure email solutions since 2002, and have helped businesses send and receive secure emails on any web browser or mobile device. NeoCertified also works across all email providers to give businesses the flexibility and assured protection they desire and deserve.Starting Price: $99.00/year/user -
2
Spike
Spike
Spike brings your entire workspace into your Inbox: email, chat, calendar, calls, team collaboration, tasks — to one powerful Inbox. Everything you need to get your work done is in a single feed, so you can finally give the app-switching a rest. Spike’s conversational email fuses traditional email with instant messaging — eliminating cluttered email threads. With real-time conversations and live collaboration, have better interactions and a more human communication experience. Spike is available on iOS, Android, Mac, Windows & Web.Starting Price: Free -
3
Delivery Trust
Identillect Technologies
Senders maintain complete control - restrict recipients’ privileges to print, forward or download content, and retract at any time. Identillect evolves with regulatory changes, continuously researching so you don’t have to. Simple for both senders and receivers. No registration or subscription required for recipients. Leverage Identillect’s patented vCard technology to further streamline your secure communications directly from Outlook. Set the level of security desired, enforce enterprise policies across the entire network limiting recipient permissions. This add-in includes access to all Delivery Trust® – Web Only features and capabilities. The DELIVERY TRUST® O365 Add-in makes securing your communications and responses simple while on the go. The intuitive interface means no learning curve with non-invasive implementation company-wide. This add-in includes access to all DELIVERY TRUST® – Web Only features and capabilities.Starting Price: $5.95 per month -
4
SecurityGateway™ for Email Servers
MDaemon Technologies
Developed by MDaemon Technologies, an email industry pioneer, Security Gateway's email threat detection technology has been protecting email servers from viruses, spam, phishing, data loss and other threats for over 20 years. Simply put, companies trust our expertise to help keep email communications safe. We protect all email platforms including Microsoft Exchange, Office 365 and others. Let our team of email security experts take the headache out of managing your company's email security needs. Security Gateway uses the latest email threat detection technology and policy enforcement tools to keep good emails flowing to and from your users. The Security Gateway cloud service can be deployed quickly and easily, allowing you to focus on other important tasks. Watch a short video to learn about some of the Security Gateway features.Starting Price: $1 per user per month -
5
Spambrella
Spambrella
Dynamically classify imposter email. Preemptively identify and sandbox suspicious URLs. Leverage big-data analysis to accurately classify bulk mail. All within a single service that connects with Microsoft 365 and Google Workspace. Spambrella’s Email Security and User Awareness Training technology is used by some of the World’s largest and most successful security-conscious companies in a multitude of continents and environments. Delivered on a global scale, Spambrella is ready to unify your email security and user awareness training requirements. Think of us as your outsourced email security team! We have deep technical expertise of all other service providers such as MxLogic, Mimecast, Symantec.cloud and know how to migrate you effortlessly. Schedule a demo today with our cybersecurity experts to uncover email threats targeting your email users.Starting Price: $1.00 -
6
LuxSci
Lux Scientiae
LuxSci provides HIPAA-compliant web and email communications services. LuxSci creates uniquely secure and customizable enterprise-grade environments and solutions that enable organizations to confidently meet their specific business and security needs at scale. LuxSci’s HIPAA-compliant email and web solutions are HITRUST certified and include: • Secure High Volume Sending for delivering massive volumes of transactional and marketing emails. • Secure SMTP Connector for encrypting outbound emails sent from Microsoft 365 and Google Workspace. • Secure Email Marketing platform for creating and sending marketing campaigns with ePHI. • Secure Email Hosting for reliable and secure day-to-day business email. • Fully managed Secure Web and Database Hosting for web applications that require compliance. • Secure Forms to safely collect and store sensitive information. LuxSci provides a full suite of secure technology for companies requiring compliant web and email services.Starting Price: $4 per/user/month -
7
Mailock
Beyond Encryption
Mailock secure email empowers companies to exchange sensitive information with customers, without risking their data. It combines award-winning encryption technology with multi-factor identity authentication to protect confidential emails from cyber risk and keep customer information protected. Compose a secure email from your desktop, browser, or use rules and keywords to initiate the encryption. Set authentication challenges to verify your recipients’ identity so only the right people gain access. Keep audit trails for every message and track your recipients’ activity with real-time read notifications. Recipients can encrypt their replies for free. Empower your customers with a secure thread to your business. Deliver confidential documents to your customers at high volume with automated secure email delivery.Starting Price: $9.30 per user per month -
8
Hushmail
Hushmail
Hushmail protects your clients by adding encryption to your emails, web forms and e-signatures. It’s secure, HIPAA-compliant, and trusted by healthcare professionals worldwide. Best of all, Hushmail is easy to set up and use. Send your first encrypted email today, and set up a secure online intake form in minutes. Your Hushmail account works just like a regular email account, with added security features to help keep your data safe. Send and receive encrypted email on the web and iPhone. Access your account using Outlook, Apple Mail or your Android smartphone. Move your forms online in minutes. Hush™ Secure Forms is our secure alternative to old-fashioned paper forms and includes online signing for your most important digital forms. Switching from pen and ink to e-signatures has never been easier.Starting Price: $9.99/month/user -
9
Echoworx
Echoworx
Echoworx is a fully managed, cloud-based SaaS email encryption solution trusted by businesses worldwide. It offers 8 secure delivery methods, supports 28 languages, and features 9 authentication options, enabling secure communication anywhere, on any device. Key Features: • Multiple Secure Delivery Methods: Web Portal, S/MIME, PGP, Secure PDF, Certificate Encryption, Secure Attachment (PDF, Office, ZIP), TLS with fallback • Free Proof of Concept (POC): Experience full functionality with a risk-free trial • 24/7 Technical Support • Extensive Branding Options • Message Tracking & Recall • End-to-End Deployment: Seamless integration and setup across platforms • Advanced Authentication: Full OAuth Access, Self-Registration, SMS, Shared Secret Passphrase, SSO, System-Generated Verification Codes, Passwordless, and Multi-Factor Authentication (MFA) • Accessibility by Design • Self-Service Account Management -
10
EncryptTitan
TitanHQ
EncryptTitan is a 100% cloud based encryption system for MSPs & Enterprises that allows users to exchange information securely via email. EncryptTitan provides organizations with the tools needed to adhere to state and federal privacy regulations while protecting their organization. EncryptTitan has pre-built DLP policies and settings that will look for regular content in the message body or attachment to automatically encrypt messages. Meet compliance requirements for protecting sensitive, private information. Providing data breach protection and avoiding costly fines and penalties. The outlook plug in can be used with our keyword encryption deployment, where the user can select which emails to be encrypted for the add in. EncryptTitan helps the safeguarding of private information & avoidance of litigation & bad press which can impact customer trust. Book your demo today and learn more about EncryptTitan. -
11
Ziroh Mail
Ziroh Labs
Even if you don’t exchange confidential emails, doesn't it bother you that your email service provider has a backdoor to your emails? They can open it to any third party, anytime. They create the rules after all, with the loopholes. Do you know what a single eCommerce receipt can reveal about you? Your taste in clothes, the money in your wallet, your preferred method of payment, where you live, which device you use, and so on. Alarming isn’t it? Well, thousands of companies and scammers already are. Every little detail about you is invaluable to third parties, they will use it to get to know you better, manipulate you to buy their products and services, and sometimes impersonate you online. If you think that your email platform is foolproof, just do a simple search. All major email platforms have been hacked. Still, feel secure? A quick, easy, non-intrusive privacy layer that protects your emails wherever they are, and wherever they reach. -
12
Egress Intelligent Email Security
Egress Software Technologies
Intelligent Email Security. Our human layer security platform uses contextual machine learning, powerful encryption and analytics technologies to prevent human-activated data breaches, protect sensitive data (Egress Protect), and enable you to identify areas of risk across your email network. We use contextual machine learning and advanced DLP technologies to dynamically help employees make good security decisions. This includes detecting and preventing accidental and intentional data leaks, and ensuring the right level of protection is applied to sensitive data when it's shared with the correct recipients. We make email encryption easy using our simple plug-in or by automating protection based on your security policies. Our intelligent technology can determine the actual risk of a breach as data is shared to ensure the correct security and control is always applied. Our eDiscovery software delivers time-saving reporting and analytics across your email network. -
13
Retarus
Retarus
As a leader in information logistics, we drive communication for companies worldwide. With intelligent infrastructures, patented technology and excellent service. Because the faster and more securely your information flows, the better your business runs. Are you ready for Retarus? Successful business depends on agile and secure communication processes for their digitized and automated workflows. From newsletters and order confirmations to password resets and status notifications – fast delivery of transactional emails plays an essential role in the customer journey. Retarus helps you reach 99% of all mobile networks. That means almost everyone in the world. Quickly and reliably. Read our use cases to learn how you can make your customer dialogue more profitable with enterprise SMS services. Send your personalized content reliably, even to large distribution lists. By email, fax or SMS—it’s easy with a standardized and intuitive platform. Communicate directly from your web browser. -
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Hornetsecurity Email Encryption
Hornetsecurity
Business emails often contain in-house, personal, or other sensitive content that could be intercepted and accessed without authorization if inadequately protected. Ensure all-around encrypted exchange of emails with Email Encryption from Hornetsecurity for reliable, secure email communication. Outgoing emails are automatically encrypted with one of the common encryption technologies (PGP, S/MIME, or TLS), depending on the set policy and availability of the corresponding certificates, without any further user intervention. If the sender’s public key is available, their emails are automatically decrypted and delivered to the recipient. Encryption of data has become a priority because of compliance requirements. In a business environment, the exchange of sensitive files and information takes place primarily via email communication. Encryption of the transmission path is essential to protect this data.
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