Best Data Center Security Software for Microsoft 365
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Compare the Top Data Center Security Software that integrates with Microsoft 365 as of October 2025
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This a list of Data Center Security software that integrates with Microsoft 365. Use the filters on the left to add additional filters for products that have integrations with Microsoft 365. View the products that work with Microsoft 365 in the table below.
What is Data Center Security Software for Microsoft 365?
Data center security software enables IT security professionals and organizations to secure their data center infrastructure including racks, networks, server endpoints, and more. Data center security tools provide all aspects of security for data centers. Data center security software helps protect the physical and virtual infrastructure of data centers from unauthorized access, cyber threats, and data breaches. Data center security software ensures that sensitive information and critical systems are safeguarded from external and internal threats by providing real-time alerts, logging activities, and implementing compliance with security standards. Compare and read user reviews of the best Data Center Security software for Microsoft 365 currently available using the table below. This list is updated regularly.
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phoenixNAP
phoenixNAP
phoenixNAP is a global IaaS provider delivering world-class infrastructure solutions from strategic edge locations in the U.S., Europe, Asia-Pacific, Australia, and Latin America. Specializing in performance, security, and availability, the company provides vastly redundant systems, unsurpassed security, high-density deployments, and flexibility to service from ¼ cabinets to private cage environments. Its Bare Metal Cloud solution provides access to 3rd Gen Intel® Xeon® Scalable Processors for advanced infrastructure performance and reliability. phoenixNAP offers a 100% uptime guarantee, an extensive server lineup, global connectivity options, flexible SLAs, and 24x7x365 live support to help businesses achieve their business objectives. Deploy high-performance, scalable cloud solutions for your growing IT needs, along with the security and reliability that you require at opex-friendly pricing plans.Starting Price: $0.10/hour -
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Trend Micro ServerProtect
Trend Micro
Enterprise servers can be a vulnerable, centralized point of information exchange. Even from inside the network, users or applications without adequate protection can unintentionally upload infected files to the server, which can spread to other systems that access these files. Additionally, large organizations may have hundreds or thousands of individual server machines that require monitoring, configuration, and maintenance. More importantly, today’s sophisticated attacks can target multiple points on the network and leave unseen trails of damage and the potential for re-infection. Trend Micro™ ServerProtect™ delivers the industry’s most reliable virus, spyware and rootkit protection while simplifying and automating security operations on servers. ServerProtect scans and detects malware in real time and incorporates cleanup capabilities to help remove malicious code and repair system damage. -
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Symantec Integrated Cyber Defense
Broadcom
The Symantec Integrated Cyber Defense (ICD) Platform delivers Endpoint Security, Identity Security, Information Security, and Network Security across on-premises and cloud infrastructures to provide the most complete and effective asset protection in the industry. Symantec is the first and only company to unify and coordinate security. Functions across both cloud and on-premises systems. Symantec enables enterprises to embrace the cloud as it makes sense for them, without sacrificing past investments and reliance on critical infrastructure. We know Symantec will never be your only vendor. That’s why we created Integrated Cyber Defense Exchange (ICDx), which makes it easy to integrate third-party products and share intelligence across the platform. Symantec is the only major cyber defense vendor that builds solutions to support all infrastructures, whether entirely on-premises, entirely in the cloud, or a hybrid of the two. -
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Privafy
Privafy
Data security must adapt to this world of change by protecting data-in-motion as it moves across enterprises, communications service providers, and IoT devices. For telecommunications service providers, there is CarrierEdge. Built to help carriers deliver managed security services to their customers through the cloud, enabling rapid scalability through simple, flexible licensing models. CarrierEdge provides a complete, enterprise-class security stack that protects data-in-motion as it moves between the enterprise, the carrier network, and the cloud. For IoT device manufacturers, there is MicroEdge. Designed for rapid, simple integration into existing IoT chipsets, MicroEdge delivers embedded security capabilities for data-in-motion as it moves from devices through hybrid cloud environments, allowing IoT device manufacturers to provide data security assurance to their customers at a lower price per device. -
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HyTrust
HyTrust
In a multi-cloud world where technology moves at lightning speed and security often plays catchup, organizations face the daunting challenge of eliminating the gaps and resolving the inconsistencies in policy enforcement and adherence to compliance mandates. HyTrust CloudControl provides advanced privileged user access control, policy enforcement, forensic and automated compliance for private clouds. HyTrust DataControl provides powerful data-at-rest encryption and integrated key management for workloads running in any cloud environment. Encrypting workloads helps enterprises to ensure their data is protected. One of the challenges of workload encryption is scaling the management of encryption keys. HyTrust’s mission is to make private, public and hybrid cloud infrastructure more trustworthy for enterprises, service providers and government agencies. HyTrust provides solutions that automate security controls for software-defined computing, networking and storage workloads.
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