Best Computer Security Software for Microsoft 365

Compare the Top Computer Security Software that integrates with Microsoft 365 as of October 2025

This a list of Computer Security software that integrates with Microsoft 365. Use the filters on the left to add additional filters for products that have integrations with Microsoft 365. View the products that work with Microsoft 365 in the table below.

What is Computer Security Software for Microsoft 365?

Computer security software helps protect devices, networks, and sensitive data from unauthorized access, cyberattacks, and other security threats. These tools provide a range of protective features such as antivirus, firewall, encryption, malware detection, and intrusion prevention systems. Computer security software is essential for safeguarding against viruses, ransomware, spyware, and phishing attacks, ensuring the integrity, confidentiality, and availability of data. Many security solutions also offer real-time monitoring, automated updates, and threat intelligence to detect and mitigate new vulnerabilities as they emerge. Businesses and individuals rely on computer security software to reduce risks, comply with regulations, and maintain a secure computing environment. Compare and read user reviews of the best Computer Security software for Microsoft 365 currently available using the table below. This list is updated regularly.

  • 1
    SpamTitan

    SpamTitan

    TitanHQ

    SpamTitan email security is an email spam filter for businesses, smbs, MSPs, and schools. SpamTitan email security blocks spam as well as phishing and day-zero attacks, viruses, malware, ransomware, and other email threats. Helps control mail flow, clean it, and protect against unwanted email. We provide easy-to-use yet advanced email security for businesses, smbs and MSPs that are Office365 friendly. SpamTitan - Premium functionality included: • CEO Impersonation protection • Phishing/ Spear phishing protection • Link analysis • Full Sandboxing • Zero Day Attacks protection • Mail Spooling • Spoofing protection • Malware and Ransomware protection • SPF/DKIM/DMARC checking • Encryption • Fully multitenant environment • Ability to rebrand the entire UI • Full REST API: • Comprehensive support and set up docs Try a FREE, fully supported trial of SpamTitan Email Security today.
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    Starting Price: $2.14/user/month
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  • 2
    HERE Enterprise Browser

    HERE Enterprise Browser

    Here Enterprise Inc.

    Computer security is at the core of HERE Enterprise Browser, delivering enterprise cybersecurity with advanced endpoint protection, app isolation, and Zero Trust security. Designed for corporate networks, it blocks phishing, malware, and data leaks while enabling secure browsing for sensitive systems. HERE combines secure access to legacy and cloud apps with enterprise policy enforcement, making it the best computer security solution for regulated industries and high-stakes environments.
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  • 3
    Keeper Security

    Keeper Security

    Keeper Security

    Keeper Security is transforming the way people and organizations around the world secure their passwords and passkeys, secrets and confidential information. Keeper’s easy-to-use cybersecurity platform is built on a foundation of zero-trust and zero-knowledge security to protect every user on every device. Keeper’s solution deploys in minutes and seamlessly integrates with any tech stack to prevent breaches, reduce help desk costs and ensure compliance. Trusted by millions of individuals and thousands of organizations globally, Keeper is the leader for best-in-class password and passkey management, secrets management, privileged access, secure remote access and encrypted messaging. Protect what matters at KeeperSecurity.com.
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    Starting Price: $2.00 per user, per month
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  • 4
    GlassWire

    GlassWire

    GlassWire

    Instantly see who or what your PC is talking to on GlassWire's network monitoring graph, plus see what your PC may have connected to in the past. Detect spyware, malware, badly behaving apps, and bandwidth hogs, then block their connections. Monitor other PCs on your network and get alerted when new unknown devices join your WiFi. GlassWire warns you of network related changes to your PC, or unusual changes to your apps that could indicate malware. GlassWire offer a Consumer Solution and a Business solution, to suit the needs of both personal users and IT professionals. Among the features: Real-Time Monitoring to keep an eye on active and past network activity Threat. Threat Detection. GlassWire's built-in firewall detects and blocks potential threats. Application Tracking to Identify which applications are using your network and track their usage patterns. Bandwidth Usage, to stay informed about data consumption, And many more!
    Starting Price: $35.88/year/user
  • 5
    N‑able Passportal
    N‑able™ Passportal™ provides simple yet secure password and documentation management tailored for the operations of an MSP and ITSP. The platform is cloud-based and offers channel partners automated password protection and makes storing, managing, and retrieving passwords and client knowledge quick and easy from virtually any connected device. The N‑able™ Passportal™ product suite also offers value-added service products including Documentation Manager™, Blink™ and Site™ all of which promote compliance with industry regulations and help protect businesses from data breaches, cybersecurity threats, and network vulnerabilities.
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    Starting Price: $18.00/month
  • 6
    PhishTitan

    PhishTitan

    TitanHQ

    Powerful Inline Phishing Protection for M365. Harness the power of AI and our LLM to defeat phishing. PhishTitan is next generation inline phishing protection and remediation, powered by TitanHQ, the global leaders in email cybersecurity. Our proprietary large learning model and AI integrates directly with Microsoft 365, both catching and remediating sophisticated phishing and BEC attacks that Microsoft misses. It provides users with in-the-moment warning banners to help them decide whether an email is malicious or safe, continually enhancing the human firewall. Risk free deployment in 6 minutes. PhishTitan will filter your email to identify phishing threats and protect your users and business. That’s how you AVOID that one wrong click that can lead to disaster – all it takes is 6 minutes! The TitanHQ team has been a category leader in the email security field for over 20 years. Bringing the experience of working with over 12,000 customers to our new phishing solution.
  • 7
    OneLogin

    OneLogin

    OneLogin

    Secure critical company information and empower employees with OneLogin, a trusted identity and access management (IAM) solution for the modern enterprise. Designed to strengthen enterprise security while simplifying business logins, OneLogin is an excellent solution for companies looking to enforce security policies with ease. OneLogin includes top-rated features such as single sign-on (SS), unified directory, user provisioning, adaptive authentication, mobile identitiy, compliance reporting, and more.
  • 8
    Microsoft Defender for Individuals
    Easy-to-use online protection for you, your family, and your devices with the Microsoft Defender app, now available for download with your Microsoft 365 subscription. Get one centralized view to manage and monitor your security status across your computers and phones. Protect your family and yourself from malicious online threats with help from antivirus and anti-phishing protection you can count on. Get real-time alerts with recommended actions plus information about how to stay safer online. One centralized view to monitor your online security status. See your and your family’s data and device protections in one place. Easily add or remove devices. Rest easy with malware protection for you and your family. Get continuous protection with antivirus scans on your apps and devices. Control what is scanned by identifying trusted apps and files. Stay up to date with real-time alerts on changes to your and your family’s security status.
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