Matrix Requirements vs. Paradigm 3 Comparison Chart

Jama Software® is focused on maximizing innovation success in multidisciplinary engineering organizations. Numerous firsts for humanity in fields such as fuel cells, electrification, space, software-defined vehicles, surgical robotics, and more all rely on Jama Connect® requirements management software to minimize the risk of defects, rework, cost overruns, and recalls. Using Jama Connect, engineering organizations can now intelligently manage the development process by leveraging Live Traceability™ across best-of-breed tools to measurably improve outcomes. Our rapidly growing customer base spans the automotive, medical device, life sciences, semiconductor, aerospace & defense, industrial manufacturing, consumer electronics, financial services, and insurance industries.

SPEC Innovations’ flagship model-based systems engineering solution can help your team reduce time-to-market, cost, and risk on even some of the most complex systems. This cloud or on-premise application uses a modern web browser, with an intuitive graphical user interface. Innoslate’s full lifecycle capabilities include: • Requirements Management • Documents Management • Modeling • Discrete Event Simulator • Monte Carlo Simulator • DoDAF Models and Views • Database Management • Test Management with full reports, status updates, results, and more. • Real Time Collaboration

Propel is a cloud-native Product Value Management platform that unifies PLM, QMS, and PIM in one connected system, giving manufacturers complete visibility and control across the entire product lifecycle. It provides a single source of truth for all product data, streamlines change management, strengthens quality and compliance processes, and accelerates time-to-market by eliminating the silos and manual steps that slow teams down. With a modern, flexible architecture and AI-driven automation, Propel helps organizations reduce errors, improve cross-functional alignment, and maintain a fully governed record of every decision, iteration, and release. From initial design through manufacturing, commercialization, and ongoing product improvements, Propel empowers companies to operate more efficiently, collaborate more effectively, and deliver innovative, high-quality products to customers faster and with greater confidence. Built for speed, clarity, and continuous innovation.

AlisQI is a modular, cloud-based Quality Management platform for process and batch manufacturers who want to reduce firefighting, improve predictability, and stay compliant by default. Unlike traditional EQMS platforms that were built around documents and later adapted for analytics, AlisQI was designed from the start as a data-first system. Quality, lab, and production data are structured and connected in one operational backbone. That foundation now enables practical AI capabilities inside daily workflows. Manufacturers can automatically extract data from diverse supplier COAs without predefined templates, generate structured digital forms from existing files or plain language, query their QMS conversationally, and detect recurring incident patterns across sites. Core modules include Document Control, Training, Deviations, CAPA, Audits, Risk Management, Supplier Quality, SPC, and EHS, supported by targeted out-of-the-box Solvers that address specific operational problems.

A sample tracking, test result capture, and inventory management cloud LIMS for life science research, biotech/NGS, and industrial QC labs. Includes regulatory support for CLIA, HIPAA, Part 11, and ISO 17025. Nothing is more critical to a lab’s success than the quality, security, and traceability of samples. The Lockbox LIMS system provides robust sample management functionality to laboratory professionals, giving them full visibility on every aspect of a sample’s journey, from accessioning to long-term storage. LIMS analysis is about more than just tracking results- Lockbox’s multi-layered sample storage and location management functionality allows you to define your lab’s storage framework using a variety of location options: rooms, storage units, shelves, racks, boxes, and positions.

Qualio is the leading quality and compliance platform built exclusively for emerging life sciences companies. MedTech, pharma, biotech, and diagnostics teams use Qualio to standardize quality processes, connect them to regulatory obligations, and gain real-time visibility into compliance health. With a modern eQMS at the core and Compliance Intelligence layered on top, Qualio helps teams get audit ready in weeks and stay audit ready forever — without spreadsheets, fire drills, or heavyweight GRC systems. What Qualio delivers: ✔️ Audit ready in weeks ✔️ Inspection ready anytime — no fire drills ✔️ Faster market entry ✔️ Lower total cost of compliance ✔️ Confident, risk-managed scaling

Process Street is an AI-powered compliance operations platform that automates complex workflows, enforces standards, and tracks audit data in real time. Teams use it to create structured SOPs, assign tasks, collect data, and monitor execution with intelligent oversight. From onboarding and audits to vendor management and document control, Process Street ensures every step is followed and every action is logged. Built for regulated industries like financial services, healthcare, and manufacturing, it supports frameworks such as ISO, SOC 2, SOX, and HIPAA. With role-based permissions, audit logs, and powerful integrations, Process Street replaces static documents, spreadsheets, and manual processes with a single automated system of record. Use AI to streamline approvals, catch risks early, and generate audit-ready evidence. Trusted by teams at Cargill, DoorDash, Farmers Insurance, and Hartford Healthcare.

Jellyfish, a leading Software Engineering Intelligence platform, helps engineering, product, and finance leaders build healthier, higher-performing R&D teams. We surface actionable insights on team health, investment allocation, and delivery, while offering purpose-built solutions to improve developer experience, streamline software capitalization, and measure the impact of AI tools like Copilot, Cursor, and AmazonQ. Over 500 organizations and 11,000 engineering teams—including GoodRX, Varo, Priceline, and PagerDuty—trust Jellyfish to optimize engineering operations so their teams can focus on what matters most. Learn more at jellyfish.co.

With the ever-increasing complexity of global medical device registration regulations, more companies are turning to regulatory information management systems software (RIMS software) to streamline the application life cycle and manage medical device applications. RegDesk is the most comprehensive AI-enabled RIMS platform for Medical Devices, Pharmaceuticals, and IVD companies offering enhanced performance and positive results more consistently than any standard regulatory information management solution. Our capabilities are as follows: • AI Application Builder • Regulatory Intelligence • Change Assessment • Standards Management • Country-Specific Templates • Distributor Collaboration • AI Document Management • Tracking & Reporting • Alerts and Notification • Product Management • Claims Management • EUDAMED For more information, visit our website.

Epicor Kinetic is a global, cloud-focused cognitive ERP solution built for manufacturers, driving profitability through real-time insights, people-centric AI, and seamless collaboration. Positioned at the core of your business applications, Kinetic leverages artificial intelligence to extract maximum value from your enterprise data, processes, and decision-making information. Purposely designed with deep industry expertise, it offers end-to-end capabilities for discrete, make-to-order, and mixed-mode manufacturers in the small and mid-market space. Kinetic supports the needs of leading manufacturers across multiple industries, including Industrial Machinery, Fabricated Metals, Electronics and High Tech, Plastics and Rubber, Automotive, Aerospace and Defense, Medical Device, Consumer Products, Furniture and Fixtures, Measuring and Controlling Devices, and more. Embrace future-ready business, digital transformation, and flexible deployment with this singular, AI-powered ERP solution.