AlphaGenome

AlphaGenome

Google DeepMind
Evo 2

Evo 2

Arc Institute
AlphaGenome Evo 2

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AlphaGenome:

About

AlphaGenome is a Google DeepMind API and Python toolkit for computational genomics research. Researchers submit DNA sequences or genetic variants to obtain model predictions about gene expression, RNA splicing, chromatin accessibility, transcription-factor binding, histone marks, and genome contacts. The API supports variant scoring and analyses of genomic regions in human and mouse data, with tutorials and reference materials for programmatic workflows. It can help researchers investigate how genetic changes may affect gene regulation and prioritize hypotheses for further study. Access is provided through a hosted API, with a Python package for local client-side use and notebook examples. AlphaGenome is intended for research and is not validated or approved for clinical or diagnostic use; its predictions should not be treated as clinical results.
Evo 2:

About

Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework.
AlphaGenome:

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported
Evo 2:

Platforms Supported

Windows Not Supported
Mac Not Supported
Linux Not Supported
Cloud Supported
On-Premises Not Supported
iPhone Not Supported
iPad Not Supported
Android Not Supported
Chromebook Not Supported
AlphaGenome:

Audience

Computational biologists, genomics researchers, and research teams using programmatic DNA-sequence and genetic-variant analysis.
Evo 2:

Audience

Computational biologists and genetic engineers in need of a tool to model and design biological sequences across multiple modalities, enhancing research in genomics and synthetic biology
AlphaGenome:

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported
Evo 2:

Support

Phone Support Not Supported
24/7 Live Support Not Supported
Online Supported
AlphaGenome:

API

Offers API Supported
Evo 2:

API

Offers API Not Supported
AlphaGenome:

Screenshots and Videos

Evo 2:

Screenshots and Videos

AlphaGenome:

Pricing

Free for non-commercial research use, subject to terms. Commercial research access is in private preview; commercial and enterprise workflows are also offered through Google Cloud.
Free Version Supported
Free Trial Not Supported
Evo 2:

Pricing

No information available.
Free Version Not Supported
Free Trial Not Supported
AlphaGenome:

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software
Evo 2:

Reviews/Ratings

Overall 0.0 / 5
ease 0.0 / 5
features 0.0 / 5
design 0.0 / 5
support 0.0 / 5

This software hasn't been reviewed yet. Be the first to provide a review:

Review this Software
AlphaGenome:

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Not Supported
Evo 2:

Training

Documentation Supported
Webinars Not Supported
Live Online Not Supported
In Person Supported
AlphaGenome:

Company Information

Google DeepMind
Founded: 2010
United Kingdom
deepmind.google/science/alphagenome/
Evo 2:

Company Information

Arc Institute
United States
arcinstitute.org/tools/evo
AlphaGenome:

Alternatives

AlphaGenome 2

AlphaGenome 2

Google DeepMind
Evo 2:

Alternatives

AlphaGenome:
Evo 2:
Evo Designer

Evo Designer

Arc Institute
AlphaGenome:
VarSeq

VarSeq

Golden Helix
Evo 2:
ESMC

ESMC

Biohub
AlphaGenome:
GenomeStudio

GenomeStudio

Illumina
Evo 2:
AlphaGenome:
XetaBase

XetaBase

Zetta Genomics
Evo 2:
AlphaGenome:

Categories

Evo 2:

Categories

AI Models Supported
AI Science Supported
Bioinformatics Supported
Foundation Models Supported
Molecular Modeling Supported
AlphaGenome:

Integrations

Evo Designer Not Supported
GitHub Not Supported
Google Antigravity Supported
Google Cloud Platform Supported
Google Colab Supported
Hugging Face Not Supported
NVIDIA BioNeMo Not Supported
Evo 2:

Integrations

Evo Designer Supported
GitHub Supported
Google Antigravity Not Supported
Google Cloud Platform Not Supported
Google Colab Not Supported
Hugging Face Supported
NVIDIA BioNeMo Supported
AlphaGenome:
Claim AlphaGenome and update features and information
Claim AlphaGenome and update features and information
Evo 2:
Claim Evo 2 and update features and information
Claim Evo 2 and update features and information