AlphaGenomeGoogle DeepMind
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Evo 2Arc Institute
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Related Products
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AlphaGenome:
About
AlphaGenome is a Google DeepMind API and Python toolkit for computational genomics research. Researchers submit DNA sequences or genetic variants to obtain model predictions about gene expression, RNA splicing, chromatin accessibility, transcription-factor binding, histone marks, and genome contacts. The API supports variant scoring and analyses of genomic regions in human and mouse data, with tutorials and reference materials for programmatic workflows. It can help researchers investigate how genetic changes may affect gene regulation and prioritize hypotheses for further study. Access is provided through a hosted API, with a Python package for local client-side use and notebook examples. AlphaGenome is intended for research and is not validated or approved for clinical or diagnostic use; its predictions should not be treated as clinical results.
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Evo 2:
About
Evo 2 is a genomic foundation model capable of generalist prediction and design tasks across DNA, RNA, and proteins. It utilizes a frontier deep learning architecture to model biological sequences at single-nucleotide resolution, achieving near-linear scaling of compute and memory relative to context length. Trained with 40 billion parameters and a 1 megabase context length, Evo 2 processes over 9 trillion nucleotides from diverse eukaryotic and prokaryotic genomes. This extensive training enables Evo 2 to perform zero-shot function prediction across multiple biological modalities, including DNA, RNA, and proteins, and to generate novel sequences with plausible genomic architecture. The model's capabilities have been demonstrated in tasks such as designing functional CRISPR systems and predicting disease-causing mutations in human genes. Evo 2 is publicly accessible via Arc's GitHub repository and is integrated into the NVIDIA BioNeMo framework.
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AlphaGenome:
Platforms Supported
Windows
Not Supported
Mac
Not Supported
Linux
Not Supported
Cloud
Supported
On-Premises
Not Supported
iPhone
Not Supported
iPad
Not Supported
Android
Not Supported
Chromebook
Not Supported
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Evo 2:
Platforms Supported
Windows
Not Supported
Mac
Not Supported
Linux
Not Supported
Cloud
Supported
On-Premises
Not Supported
iPhone
Not Supported
iPad
Not Supported
Android
Not Supported
Chromebook
Not Supported
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AlphaGenome:
Audience
Computational biologists, genomics researchers, and research teams using programmatic DNA-sequence and genetic-variant analysis.
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Evo 2:
Audience
Computational biologists and genetic engineers in need of a tool to model and design biological sequences across multiple modalities, enhancing research in genomics and synthetic biology
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AlphaGenome:
Support
Phone Support
Not Supported
24/7 Live Support
Not Supported
Online
Supported
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Evo 2:
Support
Phone Support
Not Supported
24/7 Live Support
Not Supported
Online
Supported
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AlphaGenome:
API
Offers API
Supported
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Evo 2:
API
Offers API
Not Supported
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AlphaGenome:
Screenshots and Videos |
Evo 2:
Screenshots and Videos |
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AlphaGenome:
PricingFree for non-commercial research use, subject to terms. Commercial research access is in private preview; commercial and enterprise workflows are also offered through Google Cloud.
Free Version
Supported
Free Trial
Not Supported
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Evo 2:
Pricing
No information available.
Free Version
Not Supported
Free Trial
Not Supported
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AlphaGenome:
Reviews/
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Evo 2:
Reviews/
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AlphaGenome:
Training
Documentation
Supported
Webinars
Not Supported
Live Online
Not Supported
In Person
Not Supported
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Evo 2:
Training
Documentation
Supported
Webinars
Not Supported
Live Online
Not Supported
In Person
Supported
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AlphaGenome:
Company InformationGoogle DeepMind
Founded: 2010
United Kingdom
deepmind.google/science/alphagenome/
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Evo 2:
Company InformationArc Institute
United States
arcinstitute.org/tools/evo
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AlphaGenome:
Alternatives |
Evo 2:
Alternatives |
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Evo 2:
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Evo 2:
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AlphaGenome:
Categories |
Evo 2:
Categories |
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AlphaGenome:
Integrations
Evo Designer
Not Supported
GitHub
Not Supported
Google Antigravity
Supported
Google Cloud Platform
Supported
Google Colab
Supported
Hugging Face
Not Supported
NVIDIA BioNeMo
Not Supported
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Evo 2:
Integrations
Evo Designer
Supported
GitHub
Supported
Google Antigravity
Not Supported
Google Cloud Platform
Not Supported
Google Colab
Not Supported
Hugging Face
Supported
NVIDIA BioNeMo
Supported
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AlphaGenome:
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Evo 2:
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