Best Blockchain Platforms for LayerZero

Compare the Top Blockchain Platforms that integrate with LayerZero as of March 2026

This a list of Blockchain platforms that integrate with LayerZero. Use the filters on the left to add additional filters for products that have integrations with LayerZero. View the products that work with LayerZero in the table below.

What are Blockchain Platforms for LayerZero?

Blockchain platforms are frameworks that allow developers to create, deploy, and manage blockchain-based applications and services. These platforms provide the underlying infrastructure for building decentralized applications (dApps), executing smart contracts, and enabling secure, transparent transactions. Blockchain platforms are typically built on distributed ledgers, which ensure data immutability, security, and decentralization. Common uses of blockchain platforms include financial services (like cryptocurrency), supply chain management, identity verification, and voting systems. Popular blockchain platforms offer support for consensus mechanisms, scalability, privacy features, and interoperability with other blockchain networks. Compare and read user reviews of the best Blockchain platforms for LayerZero currently available using the table below. This list is updated regularly.

  • 1
    Mantle

    Mantle

    Mantle

    Build dApps with exceptional UX, all while relying on Ethereum's unrivaled security, with our high-performance Ethereum layer-2 network built with modular architecture. Experience high throughput with unrivaled security with Ethereum's roll-up technology — all in a familiar EVM environment. Mantle Liquidity Staking Protocol (LSP) is the second core product of Mantle ecosystem. Stake ETH and receive yield-bearing mETH (Mantle Staked Ether). As stewards of a significant treasury, and with the power to shape economic outcomes of Mantle products, we prioritize a value-oriented mindset, transparency, and accountability.
  • 2
    Manta Network

    Manta Network

    Manta Network

    Manta Pacific leverages Celestia and a modified OP stack to deliver a cutting-edge technical infrastructure offering extraordinary scalability paired with low gas fees. Combined with Manta Pacific's universal circuits, Manta Pacific delivers an unrivaled environment for building and deploying ZK applications and dApps. From DeFi to gaming to social, apps deploying on Manta are designed to bring the best experience and value to real users. The Manta ecosystem grants program is designed to explore and grow new and valuable use cases to solve pain points faced by real users. Manta Network’s zkSBTs allow users to verify in a trustless, decentralized manner without exposing any details. zkSBTs such as the zkBAB and zkGalxe passports deliver a seamless on-chain KYC verification without any need to scan passports or enter sensitive personal information.
  • 3
    Scroll

    Scroll

    Scroll

    Scroll is designed by and for Ethereum developers. A swift, reliable and scalable Layer 2 blockchain, Scroll extends Ethereum's capabilities, enabling apps to scale without any surprises. Thanks to bytecode-level compatibility, existing Ethereum apps can migrate onto Scroll as-is, and at a significantly reduced cost. Our open development approach combines the best ideas among value-aligned contributors and leads to more secure and better-designed systems. Scroll is forging a community-driven path to redefine and evolve Ethereum’s roadmap. Scroll uses advanced zero-knowledge-proof technology, battle-tested EVM models, and rigorous audits to ensure that our foundation is rooted in security and reliability. By prioritizing code security through open source collaboration, Scroll protects our developers and users against vulnerabilities.
  • 4
    Polyhedra

    Polyhedra

    Polyhedra

    Bringing interoperability and scalability with cutting-edge zero-knowledge proof systems. zkBridge uses zkSNARKs to enable a prover to efficiently convince the receiver chain that a certain state transition happened on the sender chain. zkBridge consists of a block header relay network and an updater contract. The block header relay network retrieves the block headers from the sender chain, generates proofs of the validity of the block headers, and sends the headers along with the proofs to the updater contract (set up on the receiver chain). The updater contract maintains a light-client state. It automatically adds block headers of the sender chain once the associated proofs are verified, and updates the current main chain of the sender chain. Polyhedra Network implements infrastructures for interoperability across heterogeneous systems which guarantee strong security without extra trust assumptions.
  • 5
    Unichain

    Unichain

    Unichain

    Unichain is a DeFi-native Ethereum L2, optimized to be the home for liquidity across chains. Unichain is a decentralized finance (DeFi) platform designed as an Ethereum Layer 2 solution, focused on liquidity and cost efficiency. It offers faster, cheaper transactions with 1-second block times and aims to reduce transaction fees by 20x compared to Ethereum. Built on the OP Stack, it promotes scalability, open-source innovations, and future enhancements like Provable Block Building. Unichain targets developers and users in the DeFi space, providing resources for smart contract deployment and liquidity pool creation​. Informed by our experience building the world's largest decentralized trading protocol. Unichain is built on the OP stack. Technical innovations introduced by Unichain are open source, and available for any rollup to adopt. A network of full nodes monitors and verifies the actions of the sequencer, bringing faster transactions and more decentralization to Unichain.
  • 6
    Holograph

    Holograph

    Holograph

    Holograph is an omnichain tokenization protocol that enables asset issuers to mint natively composable omnichain tokens. It has been used to mint millions of on-chain assets, making it one of the most widely used protocols for cross-chain asset production and distribution. Holograph works by burning tokens on the source chain, sending a message via a messaging protocol to the destination chain, and then reminting the same number of tokens to the same contract address. This process unifies liquidity, eliminates slippage, and preserves fungibility across blockchains. The protocol facilitates the use of a single, unique contract address on all EVM blockchains, allowing for all subsequent contracts to be derived from them. This approach ensures that contract addresses remain the same no matter where they are deployed, supporting all existing and future EVM chains. Holograph provides a complete solution for asset issuers with a customizable infrastructure for omnichannel token creation.
  • 7
    Rootstock

    Rootstock

    Rootstock

    ​Rootstock is a pioneering Bitcoin sidechain that integrates Ethereum-compatible smart contract capabilities with Bitcoin's robust security. As an open source platform, it leverages Bitcoin's proof-of-work consensus mechanism, achieving over 60% of Bitcoin's hashing power through merged mining. This integration allows developers to deploy EVM-compatible smart contracts, enabling the creation of decentralized applications secured by Bitcoin's network. Rootstock's native currency, RBTC, is pegged 1:1 to Bitcoin, facilitating seamless interaction with DeFi protocols and dApps on the Rootstock network for activities such as minting, swaps, and gas fees. The PowPeg protocol ensures secure and efficient two-way transfers between Bitcoin and Rootstock, enhancing interoperability. Rootstock's ecosystem encompasses a diverse range of applications, from swapping and staking with platforms like Sushi to yield optimization with Beefy and trading on Oku.
  • 8
    Hemi

    Hemi

    Hemi

    Hemi is a breakthrough modular Layer-2 blockchain protocol that seamlessly merges Bitcoin’s rock-solid security with Ethereum’s versatile programmability by embedding a full Bitcoin node into an Ethereum-compatible EVM, known as the Hemi Virtual Machine (hVM). This architecture allows developers to write Solidity smart contracts that natively access Bitcoin data without relying on bridges or synthetic assets. Using its proprietary Proof-of-Proof (PoP) consensus, Hemi achieves “superfinality,” anchoring transactions in Bitcoin blocks for high integrity and resistance to reorgs, all while maintaining fast finality. Its Hemi Bitcoin Kit (hBK) gives developers the tools to build truly Bitcoin-powered DeFi applications, such as lending, staking, automated market makers, MEV systems, and multi-chain DAOs, using real BTC as collateral or yield sources.
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