Best On-Premises Bioinformatics Software

Sapio Sciences' mission is to improve lives by accelerating discovery, and because science is complex, Sapio makes technology simple. Sapio is a global business offering an all-in-one science-awareTM lab informatics platform combining cloud-based LIMS, ELN, and the Sapio Scientific Data Cloud. Sapio serves some of the largest global and specialist brands, including biopharma, CRO/CDMOs, and clinical diagnostic labs across NGS genomic sequencing, bioanalysis, bioprocessing, chemistry, stability, histopathology, in vivo studies, and manufacturing. Customers love Sapio's platform because it is robust, scalable, and can quickly adapt to meet unique needs. The only true platform fully no-code/low-code configurable, enabling labs to easily adapt workflows and features without extensive vendor involvement. Robust integrations with laboratory instruments, ERP, and enterprise systems; supports APIs and webhook connectivity. Many solutions off the shelf.

The Illumina DRAGEN Secondary Analysis provides accurate, comprehensive, and efficient analysis of next-generation sequencing data. Graph reference genome and machine learning driving unprecedented accuracy. Provides ultra-efficient workflow; can fully process a 34x whole human genome in ~30 minutes with DRAGEN server v4. Furthers ultra-efficient workflow by reducing FASTQ file sizes up to 5×. Analyzes next-generation sequencing (NGS) data from whole genomes, exomes, methylomes, and transcriptomes. Available on platform of choice and scalable based on needs. DRAGEN analysis leads in accuracy for germline and somatic variant calling demonstrated in industry challenges from precisionFDA. DRAGEN analysis enables labs of all sizes and disciplines to do more with their genomic data. DRAGEN analysis uses highly reconfigurable field-programmable gate array technology (FPGA) to provide hardware-accelerated implementations of genomic analysis algorithms.

Simple, fast, and repeatable variant analysis software for gene panels, exomes, and whole genomes. VarSeq is an intuitive, integrated software solution for tertiary analysis. With VarSeq you can automate your workflows and analyze variants for gene panels, exomes, and whole genomes. Understanding genomic data has never been easier thanks to our software. VarSeq software provides a powerful filtering and annotation engine to sift through large variant data sets. Using a chain of filters, you can quickly narrow your list of variants down to those that are most likely to be of interest. After determining the parameters that work well for your analysis, you can save the state of your filters so that you can easily apply the same analysis to another dataset. The same automated workflow can be used for each batch of samples, making VarSeq an ideal solution for high-throughput environments. Real-time filtering gives you the power to quickly prototype and tune analysis workflows.

With its comprehensive suite of integrated software, StarDrop™ delivers best-in-class in silico technologies within a highly visual and user-friendly interface. StarDrop™ enables a seamless flow from the latest data through predictive modeling to decision-making regarding the next round of synthesis and research, improving the speed, efficiency, and productivity of the discovery process. Successful compounds require a balance of many different properties. StarDrop™ guides you through this multi-parameter optimization challenge to target compounds with the best chance of success, saving you time and resources by enabling you to synthesize and test fewer compounds.

​Seqera is a bioinformatics platform developed by the creators of Nextflow, designed to streamline and enhance the management of scientific data analysis workflows. It offers a comprehensive suite of tools, including the Seqera Platform for orchestrating scalable data pipelines, Seqera Pipelines for accessing a curated collection of open source workflows, Seqera Containers for simplifying container management, and Seqera Studios for interactive data analysis environments. It supports seamless integration with various cloud and on-premises infrastructures, ensuring reproducibility and compliance in scientific research. Integrate Seqera into existing on-premises systems and cloud platforms like AWS, GCP, and Azure, with no forced migrations. Maintain full control over data residency and scale globally, without compromising security or performance.