Compare the Top Application Control Software for Mac as of June 2025

What is Application Control Software for Mac?

Application control software, sometimes referred to as application whitelisting software, provides organizations with the ability to monitor and manage applications installed on computers. It allows for the automated enforcement of regulatory compliance policies, including restricting user access to specific applications or functions. Application control software can also be used for enforcing cross-platform usage rights and tracking application resource utilization. Compare and read user reviews of the best Application Control software for Mac currently available using the table below. This list is updated regularly.

  • 1
    ManageEngine Endpoint Central
    ManageEngine's Endpoint Central (formerly Desktop Central) is a Unified Endpoint Management Solution, that takes care of enterprise mobility management (including all features of mobile application management and mobile device management), as well as client management for a diversified range of endpoints - mobile devices, laptops, computers, tablets, server machines etc. With ManageEngine Endpoint Central, users can automate their regular desktop management routines like distributing software, installing patches, managing IT assets, imaging and deploying OS, and more.
    Starting Price: $795.00/one-time
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  • 2
    Heimdal Endpoint Detection and Response (EDR)
    Empower your sysadmins and users alike with App Control. Choose from multiple options like file path, publisher, certificate, vendor name, software name, MD5, and more to effortlessly allow or block application execution. Take control of your system, your way.
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    Starting Price: $0/month
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  • 3
    ThreatLocker

    ThreatLocker

    ThreatLocker

    The ThreatLocker suite of security tools are powerful and designed so that everyone from businesses to government agencies to academic institutions can directly control exactly what applications run on their networks. We envision a future in which all organizations can chart their own course free from the influence of cybercriminals and the damage their incursions cause, and our team of veteran cybersecurity professionals created ThreatLocker to make this vision a reality. The team at ThreatLocker has been developing cybersecurity tools for decades, including programs to enhance email and content security, and this is our most innovative and ambitious cybersecurity solution yet. We developed this unique cybersecurity system because we believe that organizations should have complete control of their networks and should not have to live in fear of the next malware attack. To learn more, visit ThreatLocker.com.
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  • 4
    baramundi Management Suite

    baramundi Management Suite

    baramundi Software USA

    Modular, scalable and highly cost-effective Unified Endpoint Management system for comprehensive IT management, security and workflow automation. Modules work together via a single database in a single user interface. Select any of 18 available modules now and add others as needed for OS Install & Cloning, Patch Management, Vulnerability Management, MDM, Remote Control, Inventory, VM Management, SNMP Device Management, Application Control, Disaster Recovery, Personal Backup and more.
    Starting Price: $5000.00/one-time
  • 5
    Delinea Privilege Manager
    Privilege Manager is the most comprehensive endpoint privilege elevation and application control solution that operates at cloud speed and scale. You can prevent malware from exploiting applications by removing local administrative rights from endpoints and implementing policy-based application controls. Privilege Manager prevents malware attacks without causing any end user friction that slows productivity. Available both on-premises and in the cloud, enterprises and fast-growing teams can manage hundreds of thousands of machines through Privilege Manager. With built-in application control, real-time threat intelligence, and actionable reporting, it is easier than ever to manage endpoints and demonstrate compliance with least privilege policies to executives and auditors.
  • 6
    PC Matic

    PC Matic

    PC Matic

    PC Matic Pro's application whitelisting is a critical preventative layer of cyber-protection that resides on top of other endpoint security solutions. zero trust whitelisting solutions prevent hacking and cyber-attacks. Block all malware, ransomware, and malicious scripts from executing. Protect your business data, users, and network with our whitelist cybersecurity solution. PC Matic Pro represents a long overdue shift in the cybersecurity industry to absolute prevention. Today's threats to critical infrastructure, industry, and all levels of government demand nothing less. PC Matic Pro provides a patented default-deny security layer at the device that blocks all unknown executions without introducing headaches for IT. Unlike traditional security solutions, customer infections aren’t required to strengthen the whitelist architecture. Local overrides can be added after prevention with a focus on accuracy and without concern for responding to an already active infection.
    Starting Price: $50 per year
  • 7
    Airlock Digital

    Airlock Digital

    Airlock Digital

    Airlock Digital is an application control solution that enforces a Deny by Default security posture. It enables organizations to define trusted applications, scripts, libraries, and processes at a granular level using file hash, path, publisher, or parent process. Only those explicitly defined as trusted are allowed to execute. The platform supports Windows, macOS, and Linux systems, including legacy operating systems and operational technology (OT) environments. Airlock Digital includes allowlisting and blocklisting capabilities, integrated file reputation checks via VirusTotal, and detailed logging for audit and compliance. Exception management is supported through features such as rule-based overrides and time-bound One-Time Passwords (OTPs). Centralized policy management allows consistent enforcement across large and distributed environments. The platform is available as an on-premises deployment, in the cloud, or as a managed hosted service.
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