The 'TARGT' pipeline for Targeted Analysis of sequencing Reads for GenoTyping can be used for genotyping of MHC/HLA genes (or other genomic regions) from ancient and modern shotgun sequence data with moderate to low sequence coverage. The pipeline consists of a main bash script that calls the different steps of the pipeline and can either be called directly or submitted to a cluster queue system, as well as additional sub-scripts and files, that are required to perform the different steps. The pipeline also requires installed versions of the mapping tool Bowtie2 and samtools.

Features

  • Genotyping of HLA genes from low-coverage sequence data
  • HLA allele calling from ancient DNA
  • Works for both ancient and modern DNA data
  • Can be adapted to other target regions easily

Project Activity

See All Activity >

Follow TARGT pipeline

TARGT pipeline Web Site

Other Useful Business Software
AI-powered service management for IT and enterprise teams Icon
AI-powered service management for IT and enterprise teams

Enterprise-grade ITSM, for every business

Give your IT, operations, and business teams the ability to deliver exceptional services—without the complexity. Maximize operational efficiency with refreshingly simple, AI-powered Freshservice.
Try it Free
Rate This Project
Login To Rate This Project

User Reviews

Be the first to post a review of TARGT pipeline!

Additional Project Details

Registered

2019-08-06