REDItools are python scripts developed with the aim to study RNA editing at genomic scale by next generation sequencing data. RNA editing is a post-transcriptional phenomenon involving the insertion/deletion or substitution of specific bases in precise RNA localizations. In human, RNA editing occurs by deamination of cytosine to uridine (C-to-U) or mostly by the adenosine to inosine (A-to-I) conversion through ADAR enzymes. A-to-I substitutions may have profound functional consequences and have been linked to a variety of human diseases including neurological and neurodegenerative disorders or cancer. NGS technologies offer a unique opportunity to investigate RNA editing. REDItools are simple python scripts conceived to investigate RNA editing at large-scale.
REDItools are now hosted at https://github.com/BioinfoUNIBA/REDItools

Features

  • RNA editing

Project Activity

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Categories

Bio-Informatics

License

MIT License

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User Reviews

  • Amazing, straightforward tool for RNA editing detection! Great support form the developers.
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Additional Project Details

Operating Systems

BSD, Linux, Mac

Intended Audience

Science/Research

Programming Language

Python

Related Categories

Python Bio-Informatics Software

Registered

2015-02-23