Name | Modified | Size | Downloads / Week |
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dnagen.py | 2010-05-20 | 2.3 kB | |
res.py | 2010-05-19 | 700 Bytes | |
dnaseq.txt | 2010-05-19 | 96 Bytes | |
README.txt | 2010-05-19 | 1.6 kB | |
Totals: 4 Items | 4.7 kB | 0 |
Project Creator: Paul Barton | Carnegie Mellon University Dept. of Biological Sciences | pbarton@andrew.cmu.edu Project Link: https://sourceforge.net/projects/pybacktranslate/ Project Goal: The goal of this project is to facilitate synthetic gene design by providing a suite of tools which are currently neither well-executed nor cohesively distributed. Namely: systematic generation of amino acid sequences which can supply a given restriction site and their relative expression optimization, listing all possible restriction sites which can be present in a given amino acid sequence when back-translated, interpretation of complex and mixed sequence information, output into several formats, and integration with modern research into expression optimization which is not based on codon bias tables for multiple organisms. See http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007002 Project Status: I am developing this project on my spare time to supplement my needs in synthetic gene design. I am not an expert programmer; my primary focus and skill pertains to logarithm generation and my needs will generally be suited by interpretation of my own curated FASTA files. However, I will be expanding my abilities as I work to make a more universal system. This project was intended as a project to grow my abilities as a programmer while enhancing productivity, I hope that eventually this tool will help others and I will work to push it forward though I cannot promise that it will be rapid. If there is interest in assisting this project in any way, please contact me as I am very receptive to input.