GenoSuite is a framework developed for proteogenomic analysis. An updated GenoSuite2 is just released where FDRScore (Jones et al. Proteomics 2009) based strategy is used to integrate results from multiple search algorithms. Prokaryotic Proteogenomic Tool(PPT) is developed as a part of GenoSuite framework. PPT is for finding novel translations in prokaryotic genomes and is dependent on Mass Spectrometry based proteomics data and related genome sequence.

Some Key features of the tool are....
(1) Configured for 4 open source algorithms to perform database searching for peptide identification. Any combination of the 4 algorithm can be chosen.
(2) Lists out the genome search specific peptides(Novel peptides).
(3) Spectral matches can be visualized for the quality assessment.
(4) Lists out the novel proteins and changes in the existing protein annotations.
(5) A Visual genomic context of the novel peptides can also be generated.

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Bio-Informatics

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Registered

2011-09-07
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