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readme.mkd 2012-12-14 1.2 kB
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The beta version 0.2 of POPBAM has finally been released!

New functionality includes:

  • Three new measures of linkage disequilibrium: omega_max (Kim and Nielsen 2004), ZnS Kelly(1997) and Wall's Q (Wall 1999).

  • Haplotype-based statistics such as number of haplotypes, minimum interpopulation haplotype distance, and the site-specific extended haplotype homozygosity statistic of Tang (2007).

  • The new diverge function which can be used to calculate divergence with reference sequence (or a specified outgroup sequence) to calculate substitution rates.

  • The snp function has the ability to write raw polymorphism data to ms and SweepFinder formatted output.

Other changes and improvements to the software include:

  • The fasta function has been deprecated.

  • Version 0.2 includes an updated base-calling model that accounts for correlations in errors on the same strand during amplification.

*The second beta release includes numerous bug fixes, most importantly, in the tree and sfs functions.

In the future, the ability to read features from a GFF file is planned for release candidate 1.0.

If you would like to suggest additional functionality or become a beta-tester, please contact Dan Garrigan at dgarriga@bio.rochester.edu.

Source: readme.mkd, updated 2012-12-14