The"Amip" GUI is intended to provide code examples of the methods proposed in:
"Unsupervised image segmentation for microarray spots with irregular contours and inner holes"
authors: Bogdan Belean, Monica Borda, Jörg Ackermann, Ina Koch and Ovidiu Balacescu
Journal: BMC Bioinformatics, 2015, 16:412
https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-015-0842-3

PDE were used for grid alignment, whereas autocorrelation driven PDE and k-means clustering
were used for spot segmentation. The proposed segmentation procedure yields the spots median
intensity values for the microarray images recorded from Cy3 and Cy5 fluorescent dyes. Based on
the fold change factor, the differentially expressed genes were determined.

Both images with single spot groups and multiple spot groups (372 and 324 spots/group) can be
processed. Example of such images were taken from the GEO and SMD databases. e.g., GSM102718 - GEO experiment for single spot group.

Project Activity

See All Activity >

Follow Automatic Microarray Image Segmentation

Automatic Microarray Image Segmentation Web Site

Other Useful Business Software
Our Free Plans just got better! | Auth0 Icon
Our Free Plans just got better! | Auth0

With up to 25k MAUs and unlimited Okta connections, our Free Plan lets you focus on what you do best—building great apps.

You asked, we delivered! Auth0 is excited to expand our Free and Paid plans to include more options so you can focus on building, deploying, and scaling applications without having to worry about your security. Auth0 now, thank yourself later.
Try free now
Rate This Project
Login To Rate This Project

User Reviews

Be the first to post a review of Automatic Microarray Image Segmentation!

Additional Project Details

Registered

2016-01-04