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PAN2HGENE, a computational tool that allows identification of gene products missing from the original genome sequence, with automated comparative analysis for both complete and draft genomes, can be used to address this limitation. In this study, PAN2HGENE was used to identify new products, resulting in altering the alpha value behavior in the pangenome without altering the original genomic sequence. Our findings indicate that this tool represents an efficient alternative for comparative analysis, with a simple and intuitive graphical interface.
Features
- From pan2hgene version 1.6 generates a report on the unique genes, accessory genome, and core genome. Just like all sequences in FASTA format.
- Due to the discontinuation of the RAST batch interface the pan2gene 1.8 adopted two software to carry out the annotation process, Prokka and Patrick. The user can freely choose inside the graphical interface.
- If you have problems with the tbl2asn software troubleshooting guidelines are available in the how-to file.
- If you use the results of this application in your work, please cite: Silva de Oliveira M, Thyeska Castro Alves J, Henrique Caracciolo Gomes de Sá P, Veras AAdO (2021) PAN2HGENE–tool for comparative analysis and identifying new gene products. PLoS ONE 16(5): e0252414. https://doi.org/10.1371/journal.pone.0252414
- Visit the research group page (www.biod.ufpa.br) and follow us on instagram @biodgroup
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