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Name Modified Size InfoDownloads / Week
Additional_scripts_and_result_files_PDGF_signalling_study.zip 2015-09-24 30.5 MB
readme.txt 2015-05-24 2.0 kB
optPBN_stand_alone_v2.2.3.zip 2015-05-24 2.6 MB
optPBN_grid_based_v2.2.3.zip 2015-05-24 667.6 MB
optPBN_stand_alone_v2.2.2.zip 2015-05-24 2.6 MB
optPBN_stand_alone_v2.2.1.zip 2015-05-24 2.6 MB
optPBN_stand_alone_v2.1.1.zip 2014-11-27 2.6 MB
optPBN_stand_alone_v2.1.zip 2014-05-05 41.1 MB
optPBN_grid_based_v2.1.zip 2014-05-05 329.1 MB
Additional_Result_Files.zip 2014-05-05 10.1 MB
optPBN_stand_alone_v2.0.zip 2014-03-13 41.2 MB
optPBN_grid_based_v2.0.zip 2014-03-13 332.6 MB
optPBN_grid_based_v1.0.zip 2013-10-25 325.6 MB
optPBN_stand_alone_v1.0.zip 2013-10-25 39.9 MB
Totals: 14 Items   1.8 GB 0
====================
optPBN release note
====================

Last update: Sunday 24th May 2015
Most recent version: v2.2.3 

=============
optPBN v2.2.3
=============
- Stable pipeline to define the qualitative boundary of parameters with 4 types of flags in the rules as follows:
  1) 'C' = constant -> fixed parameter value, e.g. for inputs
  2) 'D' = default -> varied parameter value between the range of 0 to 1
  3) 'L' = low -> varied parameter value lower than the counter part 'H', will mostly fall below 0.5 (adjustable)
  4) 'H' = high -> varied parameter value higher than the counter part 'L', will mostly fall above 0.5 (adjutsable)

=============
optPBN v2.2.2
=============
- Second effort to define the qualitative boundary of parameters with actual number in the rules e.g., rules=A+B,'1','LB','UB'

=============
optPBN v2.2.1
=============
- Initial effort to manuallyn set qualitative boundary of parameters (cij) 

===========
optPBN v2.2
===========
- Integrate Chi-square calculation into the pipeline as another formula to make use of SD value to calculate fitting cost

===========
optPBN v2.1
===========
- Major revision on the approximation of steady-state probability: applied Two-state Markov chain approach (marginal distribution)
- Fixed wrong Two-state Markov chain equations in the original articles
- Remove the first version of pbnStationary script (TS) and use only the second version (TS2 -> TS)
- Condense the installation package, especially the SBtoolbox2 (include only the optimisation toolbox) -> from 100+MB -> 3MB

===========
optPBN v2.0
===========
- Bugs fixed and improved speed of computational pipeline, especially on the grid-based pipeline

===========
optPBN v1.0
===========
- Approximate steady-state distribution in multiple runs with random initial condition (no perturbation)
- 2 version of pbnStationary distribution for n<25 (TS) to calculate pmf and n>25 (TS2) to calculate pdf
Source: readme.txt, updated 2015-05-24