NanoGLADIATOR

Nano-GLADIATOR is a novel software tool that allows to analyze WGS data generated during a MinION or GridION X5 run for the detection of copy number alterations (CNAs).
Nano-GLADIATOR (Nanopore Genomic aLterations AnD allelIc frAcTiOn pRedictor) is capable to perform CNVs/CNAs detection and allelic fraction prediction during the sequencing run ("On-line" mode for real time molecular karyotyping) and once the experiment is completed ("Off-line" mode, for parallel analysis of multiple samples).
In "On-line" mode the tool must be launched simultaneously to a nanopore experiment so that, by exploiting the data flow generated during the sequencing process, it can perform real-time CNVs/CNAs detection. In "Off-line" mode Nano-GLADIATOR can be used to perform parallelized analysis of multiple runs at once for the identification of germline CNVs and somatic CNAs.

Features

Nanopore sequencing
Real time detection of Copy Number Alteration
MinION
GridION

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