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| Name | Modified | Size | Downloads / Week |
|---|---|---|---|
| Parent folder | |||
| SPCA_normalization.r | 2014-05-23 | 2.4 kB | |
| pca.training.results.OBX.1000.females.RData | 2014-05-23 | 15.8 MB | |
| gc.50k.all.RData | 2014-05-23 | 347.3 kB | |
| bin.names.61927.RData | 2014-05-23 | 143.8 kB | |
| bin.parameters.obx.1000.females.36bp.noPcrDup.stringent.RData | 2014-05-23 | 1.1 MB | |
| Totals: 5 Items | 17.4 MB | 0 | |
The data and script stored in this repository are companion information for the manuscript entitled "Detection of Fetal Subchromosomal Abnormalities by Sequencing Circulating Cell-Free DNA from Maternal Plasma" authors: Chen Zhao, John Tynan, Mathias Ehrich, Gregory Hannum, Ron McCullough, Juan-Sebastian Saldivar, Paul Oeth, Dirk van den Boom, Cosmin Deciu* Corresponding author cdeciu@sequenom.com The R scripts included in this package are: data_normalization.r The example code to perform the two step data normalization algorithm described in the paper. The R script for the normalization function and its paramter files are stored at the paramter folder. plotChromosome_function.r: The function to plot 50kb normalized bin count and the ideograms. cyto.RData: The R dataframe used by plotChromosome_function.r to get the banding coordinates. example_code_to_plot_50kb_trace.r: The example R code to take the normalized bin count and plot 50kb traces. The code has been tested with R version 2.15.0 platform x86_64-pc-mingw32 arch x86_64 os mingw32 system x86_64, mingw32 status major 2 minor 15.0 year 2012 month 03 day 30 svn rev 58871 language R version.string R version 2.15.0 (2012-03-30)
