MANTI is a one-stop shop N-termini annotation & evaluation solution. MANTI was previously (un)known as muda.pl ahead of v3.7, the project was renamed to MANTI.pl with v3.7 on 2019-06-24.

It congregates information from different MaxQuant or DiaNN/MSFragger output files into a master file suitable explicitly for protein neo-termini analyses. The central anchor for the data congregation is the modificationSpecificPeptides.txt or diann-output.pr_matrix.tsv file - additional data is inferred from different other source files from the corresponding folder. Maybe also useful for normal proteomics purposes but this script is heavily optimized for protein neo-termini identification and validation. A graphical interface is available as Yoğurtlu_MANTI (a Perl/Tk script) + execut. application versions for Win1x without the need to have Perl installed locally.
For a very detailed explanation of script parameters and the evaluation strategy, please consult the extensive manual PDF

Features

  • Mastering Advanced N-Termini Interpretation
  • MaxQuant N-termini evaluation
  • DiaNN/MSFragger DIA N-termini data validation & analysis
  • Protein-Termini evaluation & validation
  • (UniProt) data annotation & assembly
  • Limma, LOCALIZER, TargetP2.0 & TopFINDer integration
  • Re-mapping of identified Termini to correct Isoforms
  • Plenty of visualization options with supplied R scripts

Project Samples

MANTI's polvops N-termini-specific volcano on the VPE0/WT HUNTER tutorial data Separation of cleavages among different localizations for different N-termini categories MANTI's validation and processing of the N-terminal peptides

Project Activity

See All Activity >

Categories

Bio-Informatics, Data Labeling

License

Artistic License 2.0

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MANTI Web Site

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Additional Project Details

Intended Audience

Science/Research

User Interface

Command-line

Programming Language

Perl

Related Categories

Perl Bio-Informatics Software, Perl Data Labeling Tool

Registered

2019-06-24
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