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A tool to study fish gene pathways by search of orthologous genes

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Most of the gene regulation pathways data from experiments are drawn from humans or from species commonly used as experimental
animal models. Accordingly, the software packages to analyse these data on the basis
of specific gene identification codes (IDs) or accession numbers (AN) are not easy to
apply to other organisms that are less characterized at the genomic level. Here, we
have developed the Gene2Path programme which automatically searches pathway databases to analyse microarray data in an independent, species-specific way. We
have illustrated the method with data obtained from an immune targeted rainbow trout microarray to search for orthologous pathways defined for other well known biological species, such as zebrafish, although the software can be applied to any other case or species of interest. The Gene2Path software allows the automated searching of NCBI databases and the straightforward visualization of the data retrieved based on a
graphic network environment.

gene2path Web Site


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Additional Project Details

Intended Audience


User Interface

Web-based, Command-line

Programming Language

Unix Shell, Python



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