FusionCatcher searches for novel/known somatic fusion genes, translocations, and chimeras in RNA-seq data (paired-end reads from Illumina NGS platforms like Solexa and HiSeq) from diseased samples.
The aims of FusionCatcher are:
- very good detection rate for finding candidate fusion genes,
- very easy to use (i.e. no a priori knowledge of databases and bioinformatics is needed in order to run FusionCatcher),
- to be as automatic as possible (i.e. the FusionCatcher will choose automatically the best parameters in order to find candidate fusion genes, e.g. finding automatically the adapters, building the exon-exon junctions automatically based on the length of the input reads, etc.) while providing the best possible detection rate for finding fusion genes.
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