Mix is a tool that combines two or more draft assemblies, without relying on a reference genome and has the goal to reduce contig fragmentation and thus speed-up genome finishing. The proposed algorithm builds an extension graph where vertices represent extremities of contigs and edges represent existing alignments between these extremities. These alignment edges are used for contig extension. The resulting output assembly corresponds to a path in the extension graph that maximizes the cumulative contig length.

Please note that Mix has moved to: https://github.com/massyah/MIX

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Categories

Bio-Informatics

License

MIT License

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Additional Project Details

Intended Audience

Science/Research

Programming Language

Python

Registered

2012-06-19