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Name Modified Size Downloads / Week Status
Parent folder
README.md 2015-02-01 12.5 kB 66 weekly downloads
ANTs-2.1.0-rc3-Linux.tar.gz 2014-10-15 1.9 GB 11 weekly downloads
ANTs-2.1.0-rc3-Darwin.dmg 2014-10-15 419.5 MB 0
antsr.pdf 2013-09-16 1.2 MB 33 weekly downloads
ANTsR_1.0.tgz 2013-09-05 2.9 MB 0
ANTsR_1.0.tar.gz 2013-09-05 357.8 MB 0
ANTs-1.9.v4-Linux.tar.gz 2013-02-11 339.6 MB 0
ANTs-1.9.v4-Linux.sh 2013-02-11 339.6 MB 0
ANTs-1.9.v4-Darwin.dmg 2013-02-10 297.2 MB 0
ANTs-1.9.v4-win32.exe 2012-12-14 143.1 MB 0
ANTs-1.9.y-Linux.tar.gz 2012-08-03 300.4 MB 0
ANTs-1.9.y-Darwin.dmg 2012-08-02 257.5 MB 0
ANTs-1.9.y-win32.exe 2012-08-02 123.1 MB 0
Totals: 13 Items   4.5 GB 10

Build Status

Advanced Normalization Tools

Questions: Discussion Site or new ANTsDoc or try this version

ANTsTalk - subject to change at any moment

ANTsRegistrationTalk - subject to change at any moment

Email: antsr.me at gmail dot com

Install ANTs via pre-built: Packages @ github older versions @ sourceforge Github Releases are here thanks to Arman Eshagi.

Build ANTs from: Source-Code (recommended)

ANTs Dashboard thanks to Arman Eshagi and Hans J. Johnson

ANTs extracts information from complex datasets that include imaging (Word Cloud). Paired with ANTsR (answer), ANTs is useful for managing, interpreting and visualizing multidimensional data. ANTs is popularly considered a state-of-the-art medical image registration and segmentation toolkit. ANTsR is an emerging tool supporting standardized multimodality image analysis. ANTs depends on the Insight ToolKit (ITK), a widely used medical image processing library to which ANTs developers contribute.


Brian B. Avants - UPENN

Role: Creator, Algorithm Design, Implementation, more

Nicholas J. Tustison - UVA

Role: Compeller, Algorithm Design, Implementation Guru, more

Hans J. Johnson - UIowa

Role: Large-Scale Application, Testing, Software design

Team Members

Core: Gang Song (Originator), Philip A. Cook, Jeffrey T. Duda (DTI), Ben M. Kandel (Perfusion, multivariate analysis)

Image Registration

Diffeomorphisms: SyN, Independent Evaluation: Klein, Murphy, Template Construction (2004)(2010), Similarity Metrics, Multivariate registration, Multiple modality analysis and statistical bias

Image Segmentation

Atropos Multivar-EM Segmentation (link), Multi-atlas methods (link), Bias Correction (link), DiReCT cortical thickness (link), DiReCT in chimpanzees

Multivariate Analysis Eigenanatomy (1) (2)

Prior-Based Eigenanatomy (in prep), Sparse CCA (1), (2), Sparse Regression (link)

ImageMath Useful!

morphology, GetLargestComponent, CCA, FillHoles ... much more!

Application Domains

Frontotemporal degeneration PENN FTD center

Multimodality Neuroimaging

Lung Imaging

  • Structure
  • Perfusion MRI
  • Branching

Multiple sclerosis (lesion filling) example

Background & Theory

ANTs has won several unbiased & international competitions

Learning about ANTs

ANTs and ITK paper

Pre-built ANTs templates with spatial priors download

The ANTs Cortical Thickness Pipeline example

"Cooking" tissue priors for templates example (after you build your template)

Basic Brain Mapping example

Large deformation example

Template construction example

Automobile example

Asymmetry example

Point-set mapping which includes the PSE metric and affine and deformable registration with (labeled) pointsets or iterative closest point

Feature matching example ... not up to date ...

Chimpanzee cortical thickness example

Global optimization example

Morphing example

fMRI or Motion Correction example

fMRI reproducibility example

fMRI prediction example ... WIP ...

Cardiac example

Brain extraction example

N4 bias correction <-> segmentation example

Cortical thickness example

MALF labeling example example

Bibliography bibtex of ANTs-related papers

ANTs google scholar page

Presentations: e.g. a Prezi about ANTs (WIP)

Reproducible science as a teaching tool: e.g. compilable ANTs tutorial (WIP)

Other examples slideshow

Landmark-based mapping for e.g. hippocampus discussed here

Brief ANTs segmentation video


Google Scholar


Boilerplate ANTs

Here is some boilerplate regarding ants image processing:

We will analyze multiple modality neuroimaging data with Advanced Normalization Tools (ANTs) version >= 2.1 [1] (http://stnava.github.io/ANTs/). ANTs has proven performance in lifespan analyses of brain morphology [1] and function [2] in both adult [1] and pediatric brain data [2,5,6] including infants [7]. ANTs employs both probabilistic tissue segmentation (via Atropos [3]) and machine learning methods based on expert labeled data (via joint label fusion [4]) in order to maximize reliability and consistency of multiple modality image segmentation. These methods allow detailed extraction of critical image-based biomarkers such as volumes (e.g. hippocampus and amygdala), cortical thickness and area and connectivity metrics derived from structural white matter [13] or functional connectivity [12]. Critically, all ANTs components are capable of leveraging multivariate image features as well as expert knowledge in order to learn the best segmentation strategy available for each individual image [3,4]. This flexibility in segmentation and the underlying high-performance normalization methods have been validated by winning several internationally recognized medical image processing challenges conducted within the premier conferences within the field and published in several accompanying articles [8][9][10][11].


[1] http://www.ncbi.nlm.nih.gov/pubmed/24879923

[2] http://www.ncbi.nlm.nih.gov/pubmed/24817849

[3] http://www.ncbi.nlm.nih.gov/pubmed/21373993

[4] http://www.ncbi.nlm.nih.gov/pubmed/21237273

[5] http://www.ncbi.nlm.nih.gov/pubmed/22517961

[6] http://www.ncbi.nlm.nih.gov/pubmed/24033570

[7] http://www.ncbi.nlm.nih.gov/pubmed/24139564

[8] http://www.ncbi.nlm.nih.gov/pubmed/21632295

[9] http://www.ncbi.nlm.nih.gov/pubmed/19195496

[10] http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837555/

[11] http://nmr.mgh.harvard.edu/~koen/MenzeTMI2014.pdf

[12] http://www.ncbi.nlm.nih.gov/pubmed/23813017

[13] http://www.ncbi.nlm.nih.gov/pubmed/24830834

ANTs was supported by: R01-EB006266-01 and by K01-ES025432-01

Source: README.md, updated 2015-02-01

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