Announcing complex graphs

Protein complexes are getting more and more attention in systems biology and bioinformatics. The next release of VPLG will therefor include the option to compute complex graphs. These graphs contain the SSEs of all chains from a PDB file (instead of a single chain).

You can use complex graphs to analyze the contacts between the different sub-units of a protein complex.

These graphs can get very large, of course. Here is a first preview, the complex graph from the entire respiratory complex I from Thermus thermophilus (PDB-ID 4HEA):

Download File: '4HEA_complex_ALL_albelig_PG.png'. Complex graph, consisting of 16 chains with a total of 279 SSEs (PNG image, 14,090 x 3,807 pixels, 1.4 MB)